Archives of Gynecology and Obstetrics

, Volume 281, Issue 5, pp 811–815 | Cite as

Pregnancy outcome of patients with dermoid and other benign ovarian cysts

  • Lisa Katz
  • Amalia Levy
  • Arnon Wiznitzer
  • Eyal SheinerEmail author
Original Article



To investigate pregnancy outcome of patients with dermoid and other benign ovarian cysts.


A population-based study comparing all pregnancies of women with and without benign ovarian cysts was conducted. Deliveries occurred during the years 1988–2007 at Soroka University Medical Center. A multivariate logistic regression model, with backward elimination, was constructed to find independent risk factors associated with benign ovarian cysts.


During the study period there were 212,114 deliveries, of which 93 occurred in patients with benign ovarian cysts. Most of the lesions were benign cyatadenoma (41.9%), 36.7% were dermoid cyst, and 11.8% were adenofibroma, mostly diagnosed during cesarean delivery (76.3%). Others (12.9%) were diagnosed during pregnancy by ultrasonography and the remaining 10.8% were diagnosed before pregnancy. The mean diameter at diagnosis was 9.05 ± 7.6 cm for cystadenoma, 6.09 ± 3.0 cm for dermoid cyst and 4.55 ± 4.1 cm for adenofibroma. Only 3 cases of ovarian torsion were noted (3.2%), and 15 cases of hospitalization due to abdominal pain (16.2%). The following conditions were significantly associated with benign ovarian cysts: hypertensive disorder [odds ratio (OR) 3.05; 95% confidence interval (CI) 1.87–4.97], and maternal age (OR 1.04; 95% CI 1.01–1.07). Ovarian dermoid cyst was significantly associated with fertility treatments (8.6 vs. 2.4% OR = 3.75; 95% CI 1.1–12.2; P = 0.019). In addition, after controlling for maternal age using a multivariate analysis, fertility treatments remained significantly associated with ovarian dermoid. No significant differences were noted between the groups regarding perinatal outcomes such as birth weight, low birth weight, congenital malformations, low Apgar scores, or perinatal mortality.


The course of pregnancy of patients with dermoid and other benign ovarian cysts, including perinatal outcomes, is favorable. The cysts should be managed conservatively if possible with routine ultrasound follow up during the pregnancy since complications are extremely rare.


Dermoid cyst Benign ovarian cysts Pregnancy Cesarean delivery Perinatal outcome 



The work is supported partly by a grant from Whitman family, Ben-Gurion University of the Negev, Center for Women’s Health Studies and Promotion. The work is performed to partly fulfill the MD requirements of Lisa Katz’s at the Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Conflict of interest statement



  1. 1.
    Hill LM, Connors-beatty DJ, Nowak A, Tush B (1998) The role of ultrasonography in the detection and management of adnexal masses during the second and third trimester of pregnancy. Am J Obstet Gynecol 179:703–707CrossRefPubMedGoogle Scholar
  2. 2.
    Nair U (2005) Acute abdomen and abdominal pain in pregnancy. Curr Obstet Gynaecol 15:359–367CrossRefGoogle Scholar
  3. 3.
    Platek DN, Henderson CE, Goldberg GL (1995) The management of a persistent adnexal mass in pregnancy. Am J Obstet Gynecol 173:1236–1240CrossRefPubMedGoogle Scholar
  4. 4.
    Leiserowitz GS (2006) Managing ovarian masses during pregnancy. Obstet Gynecol Surv 61:463–470CrossRefPubMedGoogle Scholar
  5. 5.
    Caspi B, Appelman Z, Rabinerson D, Zalel Y, Tulandi T, Shoham Z (1997) The growth pattern of ovarian dermoid cysts: a prospective study in premenopausal and postmenopausal women. Fertil Steril 68:501–505CrossRefPubMedGoogle Scholar
  6. 6.
    Caspi B, Levi R, Appelman Z, Rabinerson D, Goldman G, Hagay Z (2000) Conservative management of ovarian cystic teratoma during pregnancy and labor. Am J Obstet Gynecol 182:503–505CrossRefPubMedGoogle Scholar
  7. 7.
    Parker WH, Childers JM, Canis M, Phillips DR, Topel H (1996) Laparoscopic management of benign cystic teratomas during pregnancy. Am J Obstet Gynecol 174:1499–1501CrossRefPubMedGoogle Scholar
  8. 8.
    Sherard GB 3rd, Hodson CA, Williams HJ, Semer DA, Hadi HA, Tait DL (2003) Adnexal masses and pregnancy: a 12-year experience. Am J Obstet Gynecol 189:358–362CrossRefPubMedGoogle Scholar
  9. 9.
    Schmeler KM, Mayo-Smith WW, Peipert JF, Weitzen S, Manuel MD, Gordinier ME (2005) Adnexal masses in pregnancy: surgery compared with observation. Obstet Gynecol 105:1098–1103PubMedGoogle Scholar
  10. 10.
    Hong JY (2006) Adnexal mass surgery and anesthesia during pregnancy: a 10-year retrospective review. Int J Obstet Anesth 15:212–216CrossRefPubMedGoogle Scholar
  11. 11.
    Usui R, Minakami H, Kosuge S, Iwasaki R, Ohwada M, Sato I (2000) A retrospective survey of clinical, pathologic, and prognostic features of adnexal masses operated on during pregnancy. J Obstet Gynaecol Res 26(2):89–93PubMedCrossRefGoogle Scholar
  12. 12.
    Whitecar MP, Turner S, Higby MK (1999) Adnexal masses in pregnancy: a review of 130 cases undergoing surgical management. Am J Obstet Gynecol 181(1):19–24CrossRefPubMedGoogle Scholar
  13. 13.
    Walid MS, Boddy MG (2009) Bilateral dermoid cysts of the ovary in a pregnant woman: case report and review of the literature. Arch Gynecol Obstet 279(2):105–108CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Lisa Katz
    • 1
  • Amalia Levy
    • 3
  • Arnon Wiznitzer
    • 2
  • Eyal Sheiner
    • 2
    Email author
  1. 1.Faculty of Health SciencesBen Gurion University of the NegevBe’er-ShevaIsrael
  2. 2.Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center Ben Gurion University of the NegevBe’er-ShevaIsrael
  3. 3.Department of Epidemiology and Health Services Evaluation, Faculty of Health SciencesBen Gurion University of the NegevBe’er-ShevaIsrael

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