Archives of Gynecology and Obstetrics

, Volume 280, Issue 2, pp 333–335 | Cite as

Peritoneal tuberculosis with elevated serum Ca-125 level mimicking advanced stage ovarian cancer: a case report

  • Orkun Tan
  • Edward Luchansky
  • Stephen Rosenman
  • Tarah Pua
  • Masoud Azodi
Letter to the Editor



Tuberculosis is still a common problem in immigrant population with peritoneal tuberculosis as the most common presentation of extrapulmonary disease.


A 36-year-old woman presented with abdominal distention, night sweats and weight loss. Physical examination and radiologic studies revealed ascites, omental caking and bilateral enlarged ovaries with an elevated serum Ca-125 of 353 U/mL. Acid-fast stain and culture were negative for Mycobacterium tuberculosis. Diagnostic laparoscopy and biopsy revealed multiple granulomas with epithelioid cells and caseification necrosis confirming tuberculosis. Treatment with anti-tuberculin drugs resulted in resolution of symptoms with a reduction in Ca-125 to normal.


Laparoscopic biopsy with frozen section evaluation would spare patients with peritoneal tuberculosis from unnecessary extensive surgery. Serum Ca-125 level may be useful in monitoring treatment response.


Peritoneal tuberculosis Ovarian cancer Ca-125 


Conflict of interest statement



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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Orkun Tan
    • 1
  • Edward Luchansky
    • 2
  • Stephen Rosenman
    • 2
  • Tarah Pua
    • 1
  • Masoud Azodi
    • 3
  1. 1.Department of Obstetrics and GynecologyNew York University School of MedicineNew YorkUSA
  2. 2.Department of Obstetrics and GynecologyBridgeport HospitalBridgeportUSA
  3. 3.Department of Obstetrics and GynecologyYale University School of MedicineNew HavenUSA

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