The effect of symptom duration in epithelial ovarian cancer on prognostic factors

  • Joseph Menczer
  • Angela Chetrit
  • Siegal Sadetzki
  • for the National Israel Ovarian Cancer Group
Original Article



To assess the association between duration of symptoms and main prognostic factors of invasive epithelial ovarian cancer (EOC).


The data of all histologically confirmed EOC patients diagnosed in Israel during the period 1994–1999 (n = 1,005) were retrieved from discharge summaries and admission records. Of the 371 (36.9%) patients with known presenting symptoms, the durations of 187 (50.4%) were recorded.


The most common presenting symptoms were abdominal pain (65.2%). The percentage of patients with three or more symptoms increased significantly with stage (P = 0.001). No statistically significant association between duration of symptoms and prognostic factors was found.


Our findings did not show an association between duration of symptoms and prognostic factors in EOC patients and may indicate that prognosis is not a function of delay in diagnosis.


Symptom duration Ovarian carcinoma Prognostic factors 


Conflict of interest statement



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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Joseph Menczer
    • 1
  • Angela Chetrit
    • 2
  • Siegal Sadetzki
    • 2
    • 3
  • for the National Israel Ovarian Cancer Group
  1. 1.Gynecologic Oncology Unit, Department of Obstetrics and GynecologyE. Wolfson Medical CenterHolonIsrael
  2. 2.Cancer and Radiation Epidemiology Unit, Gertner Institute for Epidemiology and Health PolicySheba Medical CenterTel HashomerIsrael
  3. 3.Sackler School of MedicineTel Aviv UniversityTel AvivIsrael

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