Feasibility and morbidity of total laparoscopic radical hysterectomy with or without pelvic limphadenectomy in obese women with stage I endometrial cancer

  • Antonio Pellegrino
  • Mauro Signorelli
  • Robert FruscioEmail author
  • Annalisa Villa
  • Alessandro Buda
  • Pietro Beretta
  • Annalisa Garbi
  • Domenico Vitobello
Original Article



The aim of this study was to describe the feasibility and morbidity rates associated with total laparoscopic radical hysterectomy (TLRH) with or without pelvic lymphadenectomy for stage I endometrial cancer in obese women.

Patients and methods

Obese patients with stage I endometrial cancer who underwent total laparoscopic radical surgery at the Department of Obstetrics and Gynecology of San Gerardo Hospital were compared to nonobese patients. The same group of obese patients was compared with patients who underwent radical laparotomic surgery. Obesity was defined as a body mass index more than 30 kg/m2.


Between September 2003 and September 2007, 75 women underwent TLRH. Median age was 54 years and median body mass index was 28 kg/m2. Thirty-seven women were obese.

There were no differences between nonobese and obese women in operative, time length of parametria and pelvic nodes removed and operative or late complications. Blood loss was significantly higher in obese patients.

Comparing retrospectively laparoscopy and laparotomy in obese women treated in our center, laparotomy was associated with decreased operative time, but also with increased blood loss, transfusion rate, duration of hospitalization and frequency of post surgical complications.


Total laparoscopic radical hysterectomy (with pelvic lymphadenectomy) is a safe option in patients with endometrial cancer. Obesity is not a contraindication to perform a TRLH with no differences in surgical parameters between obese and nonobese population. TLRH show a significant decrease of complications compared to laparotomic radical surgery in obese women.


Laparoscopy Endometrial cancer Obesity TLRH 


Conflict of interest statement

All the authors (Antonio Pellegrino, Mauro Signorelli, Robert Fruscio, Annalisa Villa, Alessandro Buda, Pietro Beretta, Annalisa Garbi and Domenico Vitobello) disclose any possibile conflict of interest.


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Antonio Pellegrino
    • 1
  • Mauro Signorelli
    • 1
  • Robert Fruscio
    • 1
    Email author
  • Annalisa Villa
    • 1
  • Alessandro Buda
    • 1
  • Pietro Beretta
    • 1
  • Annalisa Garbi
    • 1
  • Domenico Vitobello
    • 1
  1. 1.Clinica Ostetrica e Ginecologica, Division of Gynecologic Oncology, Ospedale San GerardoUniversity of Milan-BicoccaMonza, MilanItaly

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