Archives of Gynecology and Obstetrics

, Volume 274, Issue 1, pp 13–18 | Cite as

Hormonal alterations in gum disease leading to preterm labor

  • Charalambos SiristatidisEmail author
  • Christos Nisiotakis
  • Nikos Zokaris
  • Charalambos Chrelias
  • Helen Iakovidou
  • Emmanuel Salamalekis
Original Article


Most studies concerning the relationship between oral infection and systemic diseases are related to periodontal disease (gum disease), by far the most common oral infection. The term periodontal disease is used to describe a group of conditions that cause inflammation and destruction of the attachment apparatus of the teeth. Gum disease is caused by bacteria found in dental plaque and about ten species have been identified as putative pathogens in periodontal disease, mainly gram-negative rods. Actinobacillusactinomycetemcomitans, Porphyromonas gingivalis, Treponemadenticola, and Tanerella forsynthesis are the gram-negative bacteria most commonly associated with mature plaque and progressing periodontitis [1]. Furthermore, Prevotella intermedia, Streptococcus intermedius-complex, Peptostreptococcus micros, Fusobacterium nucleatum, Eubacterium nodatum, and Campylobacter rectus have shown moderate evidence for the disease etiology [2].

Periodontitis lesions exhibit gingival...


Preterm labor Gum disease Cytokines Prostaglandines 


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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Charalambos Siristatidis
    • 1
    • 2
    Email author
  • Christos Nisiotakis
    • 3
  • Nikos Zokaris
    • 3
  • Charalambos Chrelias
    • 1
  • Helen Iakovidou
    • 2
  • Emmanuel Salamalekis
    • 1
  1. 1.Third Department of Obstetrics and GynecologyUniversity of Athens, “Attikon Hospital”AthensGreece
  2. 2.AthensGreece
  3. 3.251 General Air Force HospitalAthensGreece

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