Hormonal alterations in gum disease leading to preterm labor
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Most studies concerning the relationship between oral infection and systemic diseases are related to periodontal disease (gum disease), by far the most common oral infection. The term periodontal disease is used to describe a group of conditions that cause inflammation and destruction of the attachment apparatus of the teeth. Gum disease is caused by bacteria found in dental plaque and about ten species have been identified as putative pathogens in periodontal disease, mainly gram-negative rods. Actinobacillusactinomycetemcomitans, Porphyromonas gingivalis, Treponemadenticola, and Tanerella forsynthesis are the gram-negative bacteria most commonly associated with mature plaque and progressing periodontitis . Furthermore, Prevotella intermedia, Streptococcus intermedius-complex, Peptostreptococcus micros, Fusobacterium nucleatum, Eubacterium nodatum, and Campylobacter rectus have shown moderate evidence for the disease etiology .
Periodontitis lesions exhibit gingival...
KeywordsPreterm labor Gum disease Cytokines Prostaglandines
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