Archives of Gynecology and Obstetrics

, Volume 273, Issue 4, pp 255–256 | Cite as

Failure of implanon contraception in a patient taking carbamazepin for epilepsia

  • Christian Schindlbeck
  • Wolfgang Janni
  • Klaus Friese
Case Report
First Online:
Received:
Accepted:

Abstract

Until now, no pregnancies have been reported in association with the implantable hormonal contraceptive Implanon (Organon, Roseland, NJ, USA), resulting in a pearl index of 0. We present a 24-year-old patient who conceived despite the correct application of Implanon for one and a half year. The patient was concurrently taking carbamazepin for epilepsia. Special care should be taken to patients demanding hormonal contraceptives while taking carbamezepin. Even Implanon seems to possibly fail in this combination.

Keywords

Contraception Pregnancy Implanon Etonogestrel Carbamazepin Epilepsia 
This is a preview of subscription content, log in to check access.

References

  1. Affandi B, Korver T, Geurts TB, Coelingh Bennink HJ, (1999) A pilot efficacy study with a single-rod contraceptive implant (Implanon) in 200 Indonesian women treated for < or =4 years. Contraception 59:167–174CrossRefPubMedGoogle Scholar
  2. Bennink HJ (2000) The pharmacokinetics and pharmacodynamics of Implanon, a single-rod etonogestrel contraceptive implant. Eur J Contracept Reprod Health Care 5(suppl 2):12–20PubMedGoogle Scholar
  3. Croxatto HB, Urbancsek J, Massai R, Coelingh BH, van Beek A. (1999) A multicentre efficacy and safety study of the single contraceptive implant Implanon. Implanon Study Group. Hum Reprod 14:976–981Google Scholar
  4. Edwards JE, Moore A (1999) Implanon. A review of clinical studies. Br J Fam Plann 24:3–16Google Scholar
  5. Glasier A (2002) Implantable contraceptives for women: effectiveness, discontinuation rates, return of fertility, and outcome of pregnancies. Contraception 65:29–37CrossRefPubMedGoogle Scholar
  6. Hansen TH, Lundvall F (1997) Factors influencing the reliability of oral contraceptives. Acta Obstet Gynecol Scand 76:61–64PubMedGoogle Scholar
  7. Jordan A (2002) Toxicology of progestogens of implantable contraceptives for women. Contraception 65:3–8CrossRefPubMedGoogle Scholar
  8. Kennedy H, Murnaghan M (2001) Implanon: when is the ideal time to insert? J Fam Plann Reprod Health Care 27:158CrossRefPubMedGoogle Scholar
  9. Le J, Tsourounis C (2001) Implanon: a critical review. Ann Pharmacother 35:329–336CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Christian Schindlbeck
    • 1
  • Wolfgang Janni
    • 1
  • Klaus Friese
    • 1
  1. 1.FrauenklinikLudwig-Maximilians-UniversityMunichGermany

Personalised recommendations