Archives of Dermatological Research

, Volume 311, Issue 3, pp 221–230 | Cite as

Willingness to pay and quality of life in patients with pruritic skin disorders

  • Maria Stefanidou
  • Georgios Evangelou
  • Nikolaos Kontodimopoulos
  • Dimitra KoumakiEmail author
  • Sabine-Elke Krueger-Krasagakis
  • Gil Yosipovitch
  • Konstantinos Krasagakis
Original Paper


Pruritic dermatosis is a frequent and burdensome disease. The objectives of this study were (1) to assess the willingness to pay (WTP) and the health-related quality of life (HRQoL) in patients with pruritic dermatoses and (2) to compare the results with data on socio-demographic data, and clinical features/symptoms of the patients. One hundred and three patients with pruritic dermatosis had participated in a non-interventional, cross-sectional study. Socio-demographic data, clinical features/symptoms, a health-related quality of life (HRQoL)-based and a dermatology-specific instrument (SF-6D and DLQI, respectively), and two utility indicators such as rating scale (RS) and time-trade-off (TTO) as well as willingness to pay (WTP) were recorded. In our study, there was a significant correlation between DLQI scores and WTP (p < 0.001). Time-trade-off (TTO) was also statistically correlated with SF-6D (p = 0.001). Regression models showed that daily duration and pruritus intensity were associated with lower HRQoL. Furthermore, WTP was the only measure revealing demographic and socio-economic characteristics such as age, education level, family status and income as predicting factors. No significant differences between groups of varying skin diseases were observed. HRQoL and WTP proved to be valid tools to assess the burden of disease in patients with pruritic dermatosis. However, further research with a larger number of patients is needed to validate the present findings.


Health-related quality of life SF-6D DLQI Time-trade-off Willingness to pay 



No funding has supported this work.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Informed consent was obtained from all the participants in this study.

Ethical approval

Ethical approval was obtained for this study.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Maria Stefanidou
    • 1
    • 2
  • Georgios Evangelou
    • 1
  • Nikolaos Kontodimopoulos
    • 2
  • Dimitra Koumaki
    • 1
    Email author
  • Sabine-Elke Krueger-Krasagakis
    • 1
  • Gil Yosipovitch
    • 3
  • Konstantinos Krasagakis
    • 1
  1. 1.Department of DermatologyUniversity Hospital of HeraklionCreteGreece
  2. 2.Faculty of Social SciencesHellenic Open UniversityPatraGreece
  3. 3.University of Miami, Hospital and ClinicsMiamiUSA

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