Skin barrier and microbiome in acne

Review

Abstract

Acne is an immune-mediated chronic inflammatory disease. Although several factors are involved in its pathophysiology, this process is not completely understood. Androgen hormone activity increases sebum production inside the pilosebaceous follicle, adjusting the environment for the development of Propionibacterium acnes which triggers inflammation. Knowing how others factors such as the skin barrier and microbiome are involved in acne, can help in understanding more about the disease and may help to conduct a better treatment.

Keywords

Acne Skin barrier Microbiome Microbiota 

Notes

Compliance with ethical standards

Conflict of interest

Authors declare that they have no conflicts of interest.

Funding

None.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2017

Authors and Affiliations

  1. 1.Federal University of São Paulo (Escola Paulista de Medicina—Universidade Federal de São Paulo)São PauloBrazil

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