Archives of Dermatological Research

, Volume 304, Issue 1, pp 1–5

In search of oral psoriasis

  • P. D. Yesudian
  • R. J. G. Chalmers
  • R. B. Warren
  • C. E. M. Griffiths
Review Article

Abstract

Even though psoriasis is a common skin disorder, reports of it involving the oral cavity are exceedingly rare, with less than 100 publications in the literature. Biopsy-proven oral psoriasis has been reported in the oral medical literature, but the commonest oral mucosal findings in most studies are associated non-specific features including fissured and geographic tongue. Case series on this entity have not provided any definitive data to support its existence. From the evidence available to date, it is still unclear if oral psoriasis is a distinct entity or if, indeed, it exists.

Keywords

Oral psoriasis Oral manifestations and psoriasis Mucocutaneous psoriasis 

References

  1. 1.
    Allen M, Ishida-Yamamoto A, McGrath J, Davison S, Iizuka H, Simon M, Guerrin M, Hayday A, Vaughan R, serre G, Trembath R, Barker J (2001) Corneodesmosin expression in psoriasis vulgaris differs from normal skin and other inflammatory skin disorders. Lab Invest 81:969–976PubMedGoogle Scholar
  2. 2.
    Ariyawardana A, Tilakaratne WM, Ranasinghe AW, Dissanayake M (2004) Oral psoriasis in an 11-year-old child: a case report. Int J Paediatr Dent 14:141–145PubMedCrossRefGoogle Scholar
  3. 3.
    Baker H, Ryan TJ (1968) Generalised pustular psoriasis. A clinical and epidemiological study of 104 cases. Br J Dermatol 80:771–793PubMedCrossRefGoogle Scholar
  4. 4.
    Binmadi NO, Jham BC, Meiller TF, Scheper MA (2010) A case of a deeply fissured tongue. Oral Surg Oral Med Oral Pathol Oral Rad 109:659–663CrossRefGoogle Scholar
  5. 5.
    Brenner S, Lipitz R, Ilie B, Krakowski A (1982) Psoriasis of the lips: the unusual Koebner phenomenon caused by protruding upper teeth. Dermatologica 164:413–416PubMedCrossRefGoogle Scholar
  6. 6.
    Bruce AJ, Rogers RS (2003) Oral psoriasis. Dermatol Clin 21:99–104PubMedCrossRefGoogle Scholar
  7. 7.
    Büchner A, Begleiter A (1976) Oral lesions in psoriatic patients. Oral Surg Oral Med Oral Pathol 41:327–332PubMedCrossRefGoogle Scholar
  8. 8.
    Costa SC, Hirota SK, Takahashi MD, Andrade H Jr, Migliari DA (2009) Oral lesions in 166 patients with cutaneous psoriasis: a controlled study. Med Oral Pathol Oral Cir Bucal 14:e371–e375Google Scholar
  9. 9.
    Daneshpazhooh M, Moslehi H, Akhyani M, Etesami M (2004) Tongue lesions in psoriasis: a controlled study. BMC Dermatology 4:16PubMedCrossRefGoogle Scholar
  10. 10.
    Dawson TA (1974) Tongue lesions in generalised pustular psoriasis. Br J Dermatol 91:419–424PubMedCrossRefGoogle Scholar
  11. 11.
    DeGregori G, Pippen R, Davies E (1971) Psoriasis of the gingiva and the tongue: report of a case. J Periodontol 42:97–100PubMedGoogle Scholar
  12. 12.
    Dendy RA, Walker GB, Harrison PV (1985) The buccal mucosa in erythrodermic psoriasis. Clin Exp Dermatol 10:495–498PubMedCrossRefGoogle Scholar
  13. 13.
    Eastman JR, Goldblatt LI (1983) Psoriasis. Palatal manifestations and physiological considerations. J Periodontol 54:736–739PubMedGoogle Scholar
  14. 14.
    Eidelman E, Chosack A, Cohen T (1976) Scrotal tongue and geographic tongue: polygenic and associated traits. Oral Surg Oral Med Oral Pathol 42:591–596PubMedCrossRefGoogle Scholar
  15. 15.
    Elliott JR, Bowers GM, Corio RL (1985) The clinical problem of oral psoriasis. Ear Nose Throat J 64:223–227PubMedGoogle Scholar
  16. 16.
    Espelid M, Bang G, Johannessen AC, Leira JI, Christensen O (1991) Geographic stomatitis: report of 6 cases. J Oral Pathol Med 20:425–428PubMedCrossRefGoogle Scholar
  17. 17.
    Gonzaga HF, Torres EA, Alchorne MM, Gerbase-Delima M (1996) Both psoriasis and benign migratory glossitis are associated with HLA-Cw6. Br J Dermatol 135:368–370PubMedCrossRefGoogle Scholar
  18. 18.
    Griffiths CEM, Barker JNWN (2007) Pathogenesis and clinical features of psoriasis. Lancet 21:263–271CrossRefGoogle Scholar
  19. 19.
    Gul U, Kilic A, Gonul M, Soylu S, Bilgili S, Han O (2006) Psoriasis of the lips: an unusual localization. Int J Dermatol 45:1381–1382PubMedCrossRefGoogle Scholar
  20. 20.
    Hernandez-Perez F, Jaimes-Aveldanez A, Urquizo-Ruvalcaba Mde L, Diaz-Barcelot M, Irigoyen-Camacho ME, Vega-Memije E, Mosqueda-Taylor A (2008) Prevalence of oral lesions in patients with psoriasis. Med Oral Patol Oral Cir Bucal 13:E703–E708PubMedGoogle Scholar
  21. 21.
    Hietanen J, Salo OP, Kanerva L, Juvakoski T (1984) Study of oral mucosa in 200 consecutive patients with psoriasis. Scand J Dent Res 92:50–54PubMedGoogle Scholar
  22. 22.
    Kaur I, Handa S, Kumar B (1997) Oral lesions in psoriasis. Int J Dermatol 36:78–79PubMedCrossRefGoogle Scholar
  23. 23.
    Lier GC, Mrowietz U, Wolfart M, Warnke PH, Wiltfang J, Springer IN (2009) Psoriasis of the tongue. J Craniomaxillofac Surg 37:51–53PubMedCrossRefGoogle Scholar
  24. 24.
    Migliari DA, Penha SS, Marques MM, Matthews RW (2004) Considerations on the diagnosis of oral psoriasis: a case report. Med Oral 9:300–303PubMedGoogle Scholar
  25. 25.
    Morris LF, Philips CM, Binnie WH, Sander HM, Silverman AK, Menter MA (1992) Oral lesions in patients with psoriasis: a controlled study. Cutis 49:339–344PubMedGoogle Scholar
  26. 26.
    Nograles KE, Davidovici B, Krueger JG (2010) New insights in the immunologic basis of psoriasis. Semin Cutan Med Surg 29:3–9PubMedCrossRefGoogle Scholar
  27. 27.
    Novak N, Gros E, Bieber T, Allam JP (2010) Human skin and oral mucosal dendritic cells as ‘good guys’ and ‘bad guys’ in allergic immune responses. Clin Exp Immunol 161:28–33PubMedGoogle Scholar
  28. 28.
    Novak N, Haberstok J, Bieber T, Allam JP (2008) The immune privilege of the oral mucosa. Trends Mol Med 14:191–198PubMedCrossRefGoogle Scholar
  29. 29.
    Pisanty S, Ship II (1970) Oral psoriasis. Oral Surg Oral Med Oral Pathol 30:351–355PubMedCrossRefGoogle Scholar
  30. 30.
    Pogrel MA, Cram D (1998) Intraoral findings in patients with psoriasis with a special reference to ectopic geographic tongue (erythema circinata). Oral Surg Oral Med Oral Pathol 66:184–189CrossRefGoogle Scholar
  31. 31.
    Rahman MA, Fikree M (2000) Perioral psoriasis. J Eur Acad Dermatol Venereol 14:521–522PubMedCrossRefGoogle Scholar
  32. 32.
    Reibel J, Clausen H, Dale BA, Thacher S (1989) Immunohistochemical analysis of stratum corneum components in oral squamous epithelia. Differentiation 41:237–244PubMedCrossRefGoogle Scholar
  33. 33.
    Richardson LJ, Kratochvil FJ, Zieper MB (2000) Unusual palatal presentation of oral psoriasis. J Can Dent Assoc 66:80–82PubMedGoogle Scholar
  34. 34.
    Robinson CM, Di Biase AT, Leigh IM, Williams DM, Thornhill M (1996) Oral psoriasis. Br J Dermatol 134:347–349PubMedCrossRefGoogle Scholar
  35. 35.
    Salmon TN, Robertson GR Jr, Tracy NH, Hiatt WR (1974) Oral psoriasis. Oral Surg Oral Med Oral Pathol 38:48–54PubMedCrossRefGoogle Scholar
  36. 36.
    Sklavounou A, Laskaris G (1990) Oral psoriasis: report of a case and review of the literature. Dermatologica 180:157–159PubMedCrossRefGoogle Scholar
  37. 37.
    Tosti A, Misciali C, Cameli N, Vincenzi C (2001) Guess what! Psoriasis of the lips. Eur J Dermatol 11:589–590PubMedGoogle Scholar
  38. 38.
    Ulmansky M, Michelle R, Azaz B (1995) Oral psoriasis: report of six new cases. J Oral Pathol Med 24:42–45PubMedCrossRefGoogle Scholar
  39. 39.
    van der Wal N, van der Kwast WA, van Dijk E, van der Waal I (1988) Geographic stomatitis and psoriasis. Int J Oral Maxillofac Surg 17:106–109PubMedCrossRefGoogle Scholar
  40. 40.
    Weathers DR, Baker G, Archard HO, Burkes EJ Jr (1974) Psoriasiform lesions of the oral mucosa (with emphasis on “ectopic geographic tongue”). Oral Surg Oral Med Oral Pathol 37:872–888PubMedCrossRefGoogle Scholar
  41. 41.
    Yamada J, Amar S, Petrungaro P (1992) Psoriasis-associated periodontitis: a case report. J Periodontol 63:854–857PubMedGoogle Scholar
  42. 42.
    Yamamoto T, Nishioka K (2002) Oral psoriasis in a patient with hepatitis C virus. Eur J Dermatol 12:75–76PubMedGoogle Scholar
  43. 43.
    Younai FS, Phelan JA (1997) Oral mucositis with features of psoriasis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 84:61–67PubMedCrossRefGoogle Scholar
  44. 44.
    Zhu JF, Kaminski MJ, Pulitzer DR, Hu J, Thomas HF (1996) Psoriasis: pathophysiology and oral manifestations. Oral Dis 2:135–144PubMedCrossRefGoogle Scholar

Related articles recently published in Archives of Dermatological Research (selected by the journal’s editorial staff)

  1. 45.
    Mrowietz U, Kragballe K, Reich K, Spuls P, Griffiths CE, Nast A, Franke J, Antoniou C, Arenberger P, Balieva F, Bylaite M, Correia O, Dauden E, Gisondi P, Iversen L, Kemeny L, Lahfa M, Nijsten T, Rantanen T, Reich A, Rosenbach T, Segaert S, Smith C, Talme T, Volc-Platzer B, Yawalkar N (2011) Definition of treatment goals for moderate to severe psoriasis: a European consensus. Arch Dermatol Res 303:1–10PubMedCrossRefGoogle Scholar
  2. 46.
    Munz OH, Sela S, Baker BS, Griffiths CE, Powles AV, Fry L (2010) Evidence for the presence of bacteria in the blood of psoriasis patients. Arch Dermatol Res 302:495–498PubMedCrossRefGoogle Scholar
  3. 47.
    Sweeney CM, Tobin AM, Kirby B (2011) Innate immunity in the pathogenesis of psoriasis. Arch Dermatol Res. doi:10.1007/s00403-011-1169-1

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • P. D. Yesudian
    • 1
    • 3
  • R. J. G. Chalmers
    • 2
  • R. B. Warren
    • 2
  • C. E. M. Griffiths
    • 2
  1. 1.Betsi Cadwaladr University Health BoardBodelwyddanUK
  2. 2.Dermatological Sciences, Salford Royal NHS Foundation TrustUniversity of Manchester, Manchester Academic Health Science CentreManchesterUK
  3. 3.Department of DermatologyGlan Clwyd HospitalDenbighshireUK

Personalised recommendations