Archives of Dermatological Research

, Volume 300, Supplement 1, pp 21–30 | Cite as

Basics of laser application to dermatology

Original Paper

Abstract

Q-switched lasers, with a pulse of light sufficiently short (nanosecond-domain) is demonstrated to be useful for treatment of dermal melanocytosis, blue–black tattoos, melanocytic nevi, and solar lentigines, although transient postinflammatory hyperpigmentation usually developed in the irradiated area during the following 3–4 months. If the postinflammatory pigmentation does not disappear after 1 year, incontinentia pigmenti histologica is a possibility. However, the pigment in café-au-lait macules responds variably to treatment. Melasma shows no response to laser. Therefore, accurate diagnosis is the key to success in the laser treatment. Laser treatment of vascular lesions is based on selective absorption by blood with thermal injury to the vessel wall. Therefore, the pulse-width of the vascular-specific lasers must be longer (microsecond-domain) than that of pigment-specific lasers. Because the wavelength of the lasers for vascular lesions, however, cannot penetrate into the deep areas of the skin, not all vascular lesions can be treated. Laser or light-assisted hair removal offers an efficient way to permanently reduce excessive hair growth. Skin rejuvenation is possible by laser or pulsed light with millisecond-domain pulse-width. Because these light sources, however, cause severe damage to the skin surface, the exposure energy must be reduced and the treatment must be combined with cooling devices. Therefore, the clinical results of light-assisted skin rejuvenation are not prominent. In conclusion, the pulse-width and wavelength of the laser light are critical parameters for laser treatments. If we obtain information about these parameters for specific lasers, we can expect the results of the treatment to be positive.

Keywords

Selective photothermolysis Photoablation Q-switched laser Postinflammatory pigmentation Nevus of Ota Melasma 

References

  1. 1.
    Anderson RR, Parrish JA (1981) The optics of human skin. J Invest Dermatol 77:13–19PubMedCrossRefGoogle Scholar
  2. 2.
    Anderson RR, Parrish JA (1983) Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science 220:524–527PubMedCrossRefGoogle Scholar
  3. 3.
    Anderson RR, Margolis RJ, Watanabe S, Flotte TJ, Hruza GJ, Dover JS (1989) Selective photothermolysis of cutaneous pigmented cells by Q-switched Nd:YAG laser pulses at 1064, 532, and 355 nm. J Invest Dermatol 93:28–32PubMedCrossRefGoogle Scholar
  4. 4.
    Dierickx C, Grossman MC, Farinelli W, Anderson RR (1998) Permanent hair removal by normal-mode ruby laser. Arch Dermatol 134:837–842PubMedCrossRefGoogle Scholar
  5. 5.
    Dover JS, Margolis RJ, Polla LL, Watanabe S, Hruza GJ, Parrish JA, RR Anderson (1989) Pigmented guinea pig skin irradiated with Q-switched ruby laser pulse—morphologic and histological findings. Arch Dermatol 125:43–49PubMedCrossRefGoogle Scholar
  6. 6.
    Harber LC, Bicker DR (1981) Photosensitivity diseases: principles of diagnosis and treatment. Saunders, Philadelphia, p 87Google Scholar
  7. 7.
    Hori Y, Kawashima M, Oohara K, Kukita A (1984) Acquired, bilateral nevus of Ota-like macules. J Am Acad Dermatol 10:961–964PubMedCrossRefGoogle Scholar
  8. 8.
    Hruza GJ, Dover JS, Flotte TJ, Goetschkes M, Watanabe S, Anderson RR (1991) Q-switched ruby laser irradiation of normal human skin: histological and ultrastructural findings. Arch Dermatol 127:1799–1805PubMedCrossRefGoogle Scholar
  9. 9.
    Margolis RJ, Dover JS, Polla LL, Watanabe S, Shea CR, Hruza GJ, Parrish JA, Anderson RR (1989) Visible action spectrum for melanin-specific selective photothermolysis. Lasers Surg Med 9:389–397PubMedCrossRefGoogle Scholar
  10. 10.
    Watanabe S, Flotte TJ, McAuliffe DJ, Jacques SL (1988) Putative photoacoustic damage in skin induced by pulsed ArF excimer laser. J Invest Dermatol 90:761–766PubMedCrossRefGoogle Scholar
  11. 11.
    Watanabe S, Anderson RR, Brorson S, Dalickas G, Fujimoto JG, Flotte TJ (1991) Comparative studies of femtosecond to microsecond laser pulses on selective pigmented cell injury in skin. Photochem Photobiol 53:757–762PubMedGoogle Scholar
  12. 12.
    Watanabe S, Takahashi H (1994) Treatment of nevus of Ota with the Q-switched ruby laser. N Engl J Med 331:1745–1750PubMedCrossRefGoogle Scholar
  13. 13.
    Watanabe S, Nakai K, Ohnishi T (2006) The condition known as ‘dark rings under the eyes’ in the Japanese population is a kind of dermal melanocytosis which can be successfully treated by Q-switched ruby laser. Dermatol Surg 32:785–789PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  1. 1.Department of DermatologyTeikyo University School of MedicineTokyoJapan

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