Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair
- 902 Downloads
The appearance of hair plays an important role in people’s overall physical appearance and self-perception. Silicon (Si) has been suggested to have a role in the formation of connective tissue and is present at 1–10 ppm in hair. Choline-stabilized orthosilicic acid (“ch-OSA”) is a bioavailable form of silicon which was found to improve skin microrelief and skin mechanical properties in women with photoaged skin. The effect of ch-OSA on hair was investigated in a randomized, double blind, placebo-controlled study. Forty-eight women with fine hair were given 10 mg Si/day in the form of ch-OSA beadlets (n = 24) or a placebo (n = 24), orally for 9 months. Hair morphology and tensile properties were evaluated before and after treatment. Urinary silicon concentration increased significantly in the ch-OSA supplemented group but not in the placebo group. The elastic gradient decreased in both groups but the change was significantly smaller in the ch-OSA group (−4.52%) compared to placebo group (−11.9%). Break load changed significantly in the placebo group (−10.8%) but not in the ch-OSA supplemented group (−2.20%). Break stress and elastic modulus decreased in both groups but the change was smaller in the ch-OSA group. The cross sectional area increased significantly after 9 months compared to baseline in ch-OSA supplemented subjects but not in the placebo group. The change in urinary silicon excretion was significantly correlated with the change in cross sectional area. Oral intake of ch-OSA had a positive effect on tensile strength including elasticity and break load and resulted in thicker hair.
KeywordsHair Tensile strength Choline-stabilized orthosilicic acid Elasticity Break load
ch-OSA was developed by Dirk Vanden Berghe for Bio Minerals n.v. This study was supported by a grant of Bio Minerals n.v. The Institute Dr. Schrader (Holzminden, Germany) was contracted as an independent research organization for the recruitment of volunteers and for the analysis of hair parameters.
- 1.Austin JH (1977) Silicon levels in human tissues. Nobel Symp 255–268Google Scholar
- 8.Calomme M, Cos P, D’Haese P, Vingerhoets R, Lamberts L, De Broe M, Van Hoorebeke C, Vanden Berghe D (2000) Silicon absorption from stabilized orthosilicic acid and other supplements in healthy subjects. In: Roussel AM et al (eds) Trace elements in man and animals, vol 10. Plenum, New York, pp 1111–1114Google Scholar
- 9.Calomme MR, Wijnen P, Sindambiwe JB, Cos P, Mertens J, Geusens P, Vanden Berghe D (2002) Effect of choline stabilized orthosilicic acid on bone density in chicks. Calcif Tissue Int 70:292Google Scholar
- 12.Carlisle EM (1981) A silicon requirement for prolyl hydroxylase activity. Fed Proc 40:866Google Scholar
- 19.Feughelman M (1971) The relation between structure and the mechanical properties of keratin fibers. Appl Polym Symp 18:757Google Scholar
- 20.Feughelman M (1982) The physical properties of alpha keratin fibers. J Soc Cosmet Chem 33:385Google Scholar
- 31.Smith BL (1993) Analysis of hair element levels by age, sex, race, and hair color. In: Anke M, Meissner D, Mills CF (eds) Trace elements in man and animals, TEMA 8. Kluwer, New York, pp 1091–1093Google Scholar
- 34.Teasdale D, Philippen H, Schlüter R, Meichelbeck H, Blankenburg G (1981) Querschnittsparameter von Humanhaaren, Teil 1: Grundlagen und Meβtechniken. Ärzt Kosm 11:161–170Google Scholar
- 36.Wickett RR (1995) Measuring the mechanical strength of hair. In: Serup J, Jemec BE (eds) Handbook of non-invasive methods and the skin. CRC, Boca Raton, pp 535–541Google Scholar
- 37.Wickett RR (2000) The chemistry and physics of hair. In: Schlossman ML (ed) The chemistry and manufacture of cosmetics, vol 1, basic science. Allured Publishing, Carol Stream, pp 255–284Google Scholar
- 39.Zviak C, Bouillon C (1986) Hair treatment and hair care products. In: Zviak C (ed) The science of hair care. Marcel Dekker, New York, p 142Google Scholar