Archives of Orthopaedic and Trauma Surgery

, Volume 130, Issue 2, pp 205–208

The effects of pre-emptive analgesia with bupivacaine on acute post-laminectomy pain

  • Cengiz Mordeniz
  • Fuat Torun
  • Ahmet Faruk Soran
  • Orhan Beyazoglu
  • Hamza Karabag
  • Ahmet Cakir
  • Seyho Cem Yucetas
Orthopaedic Surgery



This is a prospective, non-randomized, hospital-based, case-controlled, clinical trial to assess the efficacy of perineural infiltration with bupivacaine at the related neural root for acute pain relief after lumbar laminectomy.


Fifty-one patients undergoing unilateral one spinal level (lumbar 4) hemi-partial laminectomy were included in the study. In 22 of the patients (Group 2), bupivacaine was infiltrated onto the neural root immediately after the exposure; the 29 patients in the control group (Group 1) were not infiltrated. All patients were monitored post-operatively regarding pain determination using a visual analog scale, and the exact time of analgesic requirement during the first post-operative day was noted. Total analgesic dose given during the first post-operative day was also recorded.


The patients who received bupivacaine infiltration intraoperatively onto the neural root (Group 2) had a statistically significantly longer time to first analgesia request (P < 0.001) and also required significantly less analgesic when compared to the control group (Group 1) (P < 0.001). Perineural bupivacaine infiltration extended the early post-operative analgesic period. While the pain was not completely suppressed, the bupivacaine infiltration helped to manage the post-operative pain more effectively.


Our data suggests that pre-emptive analgesia via perineural infiltration of bupivacaine is a simple, and effective method for post-operative acute pain relief.


Pre-emptive analgesia Bupivacaine Pain Lumbar laminectomy 


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Cengiz Mordeniz
    • 1
    • 3
  • Fuat Torun
    • 2
  • Ahmet Faruk Soran
    • 2
  • Orhan Beyazoglu
    • 1
  • Hamza Karabag
    • 2
  • Ahmet Cakir
    • 2
  • Seyho Cem Yucetas
    • 2
  1. 1.Department of Anesthesiology, Faculty of MedicineHarran UniversitySanliurfaTurkey
  2. 2.Department of Neurosurgery, Faculty of MedicineHarran UniversitySanliurfaTurkey
  3. 3.TekirdağTurkey

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