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Archives of Orthopaedic and Trauma Surgery

, Volume 129, Issue 7, pp 929–933 | Cite as

Surgical treatment for local control of extremity and trunk desmoid tumors

  • Yoji Shido
  • Yoshihiro NishidaEmail author
  • Hiroatsu Nakashima
  • Hirohisa Katagiri
  • Hideshi Sugiura
  • Yoshihisa Yamada
  • Naoki Ishiguro
Orthopaedic Surgery

Abstract

Introduction

Surgical treatment has been the mainstay for extremity and trunk desmoid tumors with a negative surgical margin. However, even when resection with a wide surgical margin is achieved, the local recurrence rate remains high. The purpose of this study was to analyze the clinical outcome of patients with extremity and trunk desmoid tumors after surgical treatment and to determine the factors influencing local recurrence.

Materials and methods

Between January 1991 and December 2003, 30 of 58 patients with desmoid tumors referred to our institutions and surgically treated and followed up for more than 2 years were selected for this study. Patient age, gender, tumor size, location, status of disease (primary or recurrent), and surgical margins were analyzed as possible risk factors for recurrence.

Results

Sixteen (53%) of the 30 patients had a local recurrence. Eight of the 19 patients (42.1%) with a negative surgical margin experienced a recurrence. Younger age (<30 years) was a significant risk factor for local recurrence (P < 0.05). Tumor size, surgical margin and previous surgical history were not associated with local recurrence. Younger age and female gender had a propensity for local recurrence, suggesting that the biological behavior of desmoid tumor may depend on the status of the disease at presentation.

Conclusions

These results suggest that radical surgical treatment causing severe functional impairment should be avoided in selected cases on the basis of patient characteristics, and that other novel therapeutic tools may be necessary for patients in whom a higher risk of local recurrence is assumed or severe complications after surgical treatment are predicted.

Keywords

Extra-abdominal desmoid Surgery Wide resection Recurrence Risk factor 

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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Yoji Shido
    • 1
  • Yoshihiro Nishida
    • 1
    Email author
  • Hiroatsu Nakashima
    • 2
  • Hirohisa Katagiri
    • 3
  • Hideshi Sugiura
    • 4
  • Yoshihisa Yamada
    • 5
  • Naoki Ishiguro
    • 1
  1. 1.Department of Orthopedic SurgeryNagoya University Graduate School of MedicineNagoyaJapan
  2. 2.Department of Orthopedic SurgeryAichi Cancer Center Aichi HospitalOkazakiJapan
  3. 3.Department of Orthopedic SurgeryShizuoka Cancer CenterNagaizumichoJapan
  4. 4.Department of Orthopedic SurgeryAichi Cancer Center Central HospitalNagoyoJapan
  5. 5.Department of Orthopedic SurgeryNagoya Memorial HospitalNagoyaJapan

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