Acta Neuropathologica

, Volume 132, Issue 5, pp 757–760 | Cite as

Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation

  • Joanna J. Phillips
  • Henry Gong
  • Katharine Chen
  • Nancy M. Joseph
  • Jessica van Ziffle
  • Lee-Way Jin
  • Boris C. Bastian
  • Andrew W. Bollen
  • Arie Perry
  • Theodore Nicolaides
  • David A. Solomon
  • Joseph T. Shieh
Correspondence

Notes

Acknowledgments

This study was funded in part by the UCSF Department of Pathology, UCSF Brain Tumor SPORE Tissue Core (NIH/NCI P50 CA097257), the Pediatric Brain Tumor Foundation (J. J. P and T. N.), and NIH/NINDS R01 (NS081117, J. J. P.). We thank and acknowledge the patients and families affected by PXA for their generous contributions to these studies.

Supplementary material

401_2016_1616_MOESM1_ESM.pdf (1 mb)
Supplementary material 1 (PDF 1074 kb)

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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Joanna J. Phillips
    • 1
    • 2
    • 3
  • Henry Gong
    • 1
  • Katharine Chen
    • 1
  • Nancy M. Joseph
    • 4
    • 5
  • Jessica van Ziffle
    • 4
  • Lee-Way Jin
    • 6
    • 7
  • Boris C. Bastian
    • 3
    • 4
  • Andrew W. Bollen
    • 2
    • 3
  • Arie Perry
    • 1
    • 2
    • 3
  • Theodore Nicolaides
    • 1
    • 8
  • David A. Solomon
    • 2
    • 3
    • 4
  • Joseph T. Shieh
    • 9
    • 10
  1. 1.Department of Neurological SurgeryUniversity of California San FranciscoSan FranciscoUSA
  2. 2.Division of Neuropathology, Department of PathologyUniversity of California San FranciscoSan FranciscoUSA
  3. 3.Helen Diller Family Comprehensive Cancer CenterUniversity of California San FranciscoSan FranciscoUSA
  4. 4.Clinical Cancer Genomics LaboratoryUniversity of California San FranciscoSan FranciscoUSA
  5. 5.Department of PathologyUniversity of California San FranciscoSan FranciscoUSA
  6. 6.Department of Pathology and Laboratory MedicineUniversity of California Davis Medical CenterSacramentoUSA
  7. 7.M.I.N.D. (Medical Investigation of Neurodevelopmental Disorders) InstituteUniversity of California Davis Medical CenterSacramentoUSA
  8. 8.Division of Pediatric Hematology/Oncology, Department of PediatricsUniversity of California San FranciscoSan FranciscoUSA
  9. 9.Division of Medical Genetics, Department of PediatricsUniversity of California San FranciscoSan FranciscoUSA
  10. 10.Institute for Human GeneticsUniversity of California San FranciscoSan FranciscoUSA

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