Histological evidence of chronic traumatic encephalopathy in a large series of neurodegenerative diseases
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Compliance with ethical standards
HL, KD, JLH and TR receive a research Grant from CBD solutions; JLH and TL receive Grants from the MSA Trust, ARUK and Parkinson’s UK. This research was partly supported by the NIHR Queen Square Biomedical Research Unit in Dementia based at University College London Hospitals, University College London. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health.
Conflict of interest
The authors declare that they have no conflict of interest.
- 4.Hazrati LN, Tartaglia MC, Diamandis P, Davis KD, Green RE, Wennberg R, Wong JC, Ezerins L, Tator CH (2013) Absence of chronic traumatic encephalopathy in retired football players with multiple concussions and neurological symptomatology. Front Hum Neurosci 7:222. doi:10.3389/fnhum.2013.00222 PubMedCentralCrossRefPubMedGoogle Scholar
- 8.Kovacs GG, Milenkovic I, Wohrer A, Hoftberger R, Gelpi E, Haberler C, Honigschnabl S, Reiner-Concin A, Heinzl H, Jungwirth S et al (2013) Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series. Acta Neuropathol 126:365–384. doi:10.1007/s00401-013-1157-y CrossRefPubMedGoogle Scholar
- 17.Tran HT, LaFerla FM, Holtzman DM, Brody DL (2011) Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-beta accumulation and independently accelerates the development of tau abnormalities. J Neurosci 31:9513–9525. doi:10.1523/JNEUROSCI.0858-11.2011 PubMedCentralCrossRefPubMedGoogle Scholar
- 18.Uryu K, Chen XH, Martinez D, Browne KD, Johnson VE, Graham DI, Lee VM, Trojanowski JQ, Smith DH (2007) Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans. Exp Neurol 208:185–192. doi:10.1016/j.expneurol.2007.06.018 PubMedCentralCrossRefPubMedGoogle Scholar