How to maximize QRS narrowing

  • Olivia Braun
  • Mate Vamos
  • Julia W. Erath
  • Stefan H. HohnloserEmail author
Case Reports



Cardiac resynchronization therapy (CRT) resulting in maximal QRS narrowing may be associated with improved outcomes.


Various atrioventricular (AV) delay settings, including the new SyncAV™ algorithm (St. Jude Medical/Abbott, St. Paul, MN, USA), aimed at maximal QRS narrowing were tested in an 81-year old CRT recipient.


Maximal QRS narrowing from 160 to 100 ms was achieved with a manually programmed value of SyncAV™ −30 ms. At 2 months, the patient proved to be a CRT super-responder.


SyncAV™ algorithm is a new way for effective QRS narrowing with potentially improved outcomes.


Cardiac resynchronization therapy Multipoint pacing QRS narrowing AV delay SyncAV™ 







Cardiac resynchronization therapy


Cardiac resynchronization therapy pacemaker


Left ventricle


Left ventricular ejection fraction


Left ventricle end diastolic diameter


Left ventricle end systolic diameter


Left ventricle end systolic volume


Multipoint pacing


New York Heart Association


Right ventricle



Methode zur Maximierung der QRS-Verschmälerung



Eine kardiale Resynchronisationstherapie (CRT) mit maximaler Verkürzung der QRS-Dauer kann mit besseren Behandlungsergebnissen einhergehen.


Diverse Programmierungen der atrioventrikulären (AV) Zeit, inklusive des neuen SyncAV™-Algorithmus (St. Jude Medical/Abbott, St. Paul, MN, USA), wurden bei einem 81-jährigen Patienten mit CRT zur Verschmälerung des QRS-Komplexes getestet.


Die maximale Verschmälerung des QRS-Komplexes von 160 auf 100 ms wurde mittels individueller SyncAV™-Programmierung auf −30 ms erreicht. Nach 2 Monaten erwies sich der Patient als „CRT-Super-Responder“.


Der SyncAV™-Algorithmus stellt eine neue Methode zur effektiven Verkürzung der QRS-Dauer dar und kann potenziell zu einer Prognoseverbesserung beitragen.


Kardiale Resynchronisationstherapie Multipoint-Stimulation Verschmälerung des QRS-Komplexes AV-Verzögerung SyncAV™ 


Compliance with ethical guidelines

Conflict of interest

O. Braun, M. Vamos, J.W. Erath and S.H. Hohnloser declare that they have no competing interests.

For this article no studies with human participants or animals were performed by any of the authors. All studies performed were in accordance with the ethical standards indicated in each case. Additional written informed consent was obtained from all individual participants or their legal representatives for whom identifying information is included in this article.


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Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2019

Authors and Affiliations

  • Olivia Braun
    • 1
  • Mate Vamos
    • 1
  • Julia W. Erath
    • 1
  • Stefan H. Hohnloser
    • 2
    Email author
  1. 1.University Hospital FrankfurtGoethe University FrankfurtFrankfurtGermany
  2. 2.Department of Cardiology, Division of Clinical Electrophysiology, University Hospital FrankfurtGoethe University FrankfurtFrankfurt am MainGermany

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