Zur Leitlinie Herzklappenerkrankungen der ESC und EACTS Version 2012
- 336 Downloads
Zusammenfassung
Herzklappenerkrankungen sind neben der koronaren Herzerkrankung die häufigsten Erkrankungen des Herz-Kreislauf-Systems. Die operative Sanierung ist heutzutage der Goldstandard. Perioperative Ergebnisse und Langzeitergebnisse sind exzellent. Eine Verbesserung der Lebensqualität der Patienten kann in den meisten Fällen dauerhaft erzielt werden. Seit wenigen Jahren sind Therapieverfahren verfügbar, die bei Aortenklappeneingriffen eine Alternative für Hochrisikopatienten darstellen, da auf die Herz-Lungen-Maschine verzichtet werden kann. Die Transkatheter-Aortenklappen-Implantation („transcatheter aortic valve implantation“, TAVI) zeigt ebenfalls gute Ergebnisse, jedoch fehlen Langzeitdaten. In diesem Beitrag werden Evidenz und Empfehlungen zur Behandlung erworbener Erkrankungen der Aortenklappe (außer der Endokarditis) sowie die Empfehlungen zur Auswahl der Klappenprothese der aktuellen Guidelines zum Management von Herzklappenerkrankungen zusammengefasst. Diese wurden erstmalig gemeinsam von der European Society of Cardiology (ESC) und der European Association of Cardiothoracic Surgery (EACTS) erstellt. In der nächsten Ausgabe der Zeitschrift für Herz-, Thorax- und Gefäßchirurgie werden dann Evidenz und Empfehlungen zur Behandlung erworbener Erkrankungen der Mitralklappe und der Trikuspidalklappe sowie zur Antikoagulation von Patienten nach Herzklappenoperationen behandelt.
Schlüsselwörter
Erworbene Erkrankungen Evidenzbasierte Medizin Interdisziplinäres Gesundheitsteam Herzklappenprothesenimplantation HerzklappenanuloplastieOn the guidelines for management of valvular heart disease of the ESC and EACTS version 2012
Abstract
Heart valve disease is the most common disease of the cardiovascular system besides coronary heart disease. Surgical intervention is currently the gold standard therapy and perioperative and long-term results are excellent. An increase in the quality of life can be durably achieved for most patients. New therapies for high-risk patients are available that can be used to treat aortic valve disease without the use of a cardiopulmonary bypass. Transcatheter aortic valve implantation (TAVI) also shows good short-term results but there is lack of comprehensive long-term results. This article summarizes the evidence and recommendations for the treatment of acquired disease of the aortic valve (except endocarditis) and for the choice of prosthesis from the recent guidelines on the management of valvular heart disease that were published for the first time together with the European Society of Cardiology (ESC) and the European Association of Cardiothoracic Surgery. In a further publication in Zeitschrift für Herz-, Thorax- und Gefäßchirurgie the evidence and recommendations for the treatment of acquired diseases of mitral and tricuspid valves and recommendations on anticoagulation for patients with prosthetic heart valves will be summarized.
Keywords
Acquired diseases Evidence based medicine Interdisciplinary health team Heart valve prosthesis implantation Cardiac valve annuloplastyNotes
Einhaltung der ethischen Richtlinien
Interessenkonflikt. S. Sündermann und V. Falk geben an, dass kein Interessenkonflikt besteht. Das vorliegende Manuskript enthält keine Studien an Menschen oder Tieren.
Literatur
- 1.Vahanian A, Alfieri O, Andreotti F et al (2012) Guidelines on the management of valvular heart disease (version 2012). Eur J Cardiothorac Surg 42:S1–S44PubMedCrossRefGoogle Scholar
- 2.Vahanian A, Alfieri O, Andreotti F et al (2012) Guidelines on the management of valvular heart disease (version 2012). Eur Heart J 33:2451–2496PubMedCrossRefGoogle Scholar
- 3.Vahanian A, Baumgartner H, Bax J et al (2007) Guidelines on the management of valvular heart disease: the Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology. Eur Heart J 28:230–268PubMedGoogle Scholar
- 4.Habib G, Hoen B, Tornos P et al (2009) Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J 30:2369–2413PubMedCrossRefGoogle Scholar
- 5.Baumgartner H, Bonhoeffer P, De Groot NM (2010) ESC Guidelines for the management of grown-up congenital heart disease (new version 2010). Eur Heart J 31:2915–2957PubMedCrossRefGoogle Scholar
- 6.Wijns W, Kolh P, Danchin N et al (2010) Guidelines on myocardial revascularization. Eur Heart J 31:2501–2555PubMedCrossRefGoogle Scholar
- 7.Dujardin KS, Enriquez-Sarano M, Schaff HV et al (1999) Mortality and morbidity of aortic regurgitation in clinical practice. A long-term follow-up study. Circulation 99:1851–1857PubMedCrossRefGoogle Scholar
- 8.Chaliki HP, Mohty D, Avierinos J-F et al (2002) Outcomes after aortic valve replacement in patients with severe aortic regurgitation and markedly reduced left ventricular function. Circulation 106:2687–2693PubMedCrossRefGoogle Scholar
- 9.Nkomo VT, Gardin JM, Skelton TN et al (2006) Burden of valvular heart diseases: a population-based study. Lancet 368:1005–1011PubMedCrossRefGoogle Scholar
- 10.European Association for Cardio-Thoracic Surgery (2010) Fourth EACTS adult cardiac surgical database report 2010. Dendrite Clinical Systems, Henley-on-Thames, UKGoogle Scholar
- 11.Society of Thoracic Surgeons (o J) Adult cardiac surgery database, executive summary, 10 years STS report. http://www.sts.orgGoogle Scholar
- 12.Bridgewater B, Keogh B, Kinsman R, Walton P (2009) The Society for Cardiothoracic Surgery in Great Britain & Ireland, 6th national adult cardiac surgical database report; demonstrating quality, 2008. Dendrite Clinical Systems, Henley-on-Thames, UKGoogle Scholar
- 13.Gummert JF, Funkat A, Beckmann A et al (2010) Cardiac surgery in Germany during 2009. A report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 58:379–386PubMedCrossRefGoogle Scholar
- 14.Van Geldorp MWA, Gameren M van, Kappetein AP et al (2009) Therapeutic decisions for patients with symptomatic severe aortic stenosis: room for improvement? Eur J Cardiothorac Surg 35:953–957CrossRefGoogle Scholar
- 15.Leon MB, Smith CR, Mack M et al; PARTNER Trial Investigators (2010) Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 363:1597–1607PubMedCrossRefGoogle Scholar
- 16.Thomas M, Schymik G, Walther TH, on behalf of the SOURCE Investigators et al (2010) Thirty-day results of the SAPIEN aortic bioprosthesis European outcome (SOURCE) registry: a European registry of transcatheter aortic valve implantation using the Edwards SAPIEN valve. Circulation 122:62–69PubMedCrossRefGoogle Scholar
- 17.Piazza N, Grube E, Gerckens U et al (2008) Procedural and 30-day outcomes following transcatheter aortic valve implantation using the third generation (18 Fr) corevalve revalving system: results from the multicentre, expanded evaluation registry 1-year following CE mark approval. EuroIntervention 4:242–249PubMedCrossRefGoogle Scholar
- 18.Thomas M, Schymik G, Walther T et al (2011) One-year outcomes of cohort 1 in the Edwards SAPIEN Aortic Bioprosthesis European Outcome (SOURCE) registry: the European registry of transcatheter aortic valve implantation using the Edwards SAPIEN valve. Circulation 124:425–433PubMedCrossRefGoogle Scholar
- 19.Buellesfeld L, Gerckens U, Schuler G et al (2011) Two-year follow-up of patients undergoing transcatheter aortic valve implantation using a self-expanding valve prosthesis. J Am Coll Cardiol 57:1650–1657PubMedCrossRefGoogle Scholar
- 20.Smith CR, Leon MB, Mack MJ et al; PARTNER Trial Investigators (2011) Transcatheter versus surgical aortic valve replacement in high-risk patients. N Engl J Med 364:2187–2198PubMedCrossRefGoogle Scholar
- 21.Zahn R, Gerckens U, Grube E et al; The German Transcatheter Aortic Valve Interventions-Registry Investigators (2011) Transcatheter aortic valve implantation: first results from a multi-center real-world registry. Eur Heart J 32:198–204PubMedCrossRefGoogle Scholar
- 22.Tamburino C, Capodanno D, Ramondo A et al (2011) Incidence and predictors of early and late mortality after transcatheter aortic valve implantation in 663 patients with severe aortic stenosis. Circulation 123:299–308PubMedCrossRefGoogle Scholar
- 23.Gurvitch R, Wood DA, Tay EL et al (2010) Transcatheter aortic valve implantation: durability of clinical and hemodynamic outcomes beyond 3 years in a large patient cohort. Circulation 122:1319–1327PubMedCrossRefGoogle Scholar
- 24.Vahanian A, Iung B, Pierard L et al (2009) Valvular heart disease. In: Camm AJ, Lüscher TF, Serruys PW (Hrsg) The ESC textbook of cardiovascular medicine, 2. Aufl. Blackwell, Malden, S 625–670Google Scholar
- 25.Rosenhek R, Binder T, Porenta G et al (2000) Predictors of outcome in severe, asymptomatic aortic stenosis. N Engl J Med 343:611–617PubMedCrossRefGoogle Scholar
- 26.Brown JM, O’Brien SM, Wu C et al (2009) Isolated aortic valve replacement in North America comprising 108,687 patients in 10 years: changes in risks, valve types, and outcomes in the Society of Thoracic Surgeons national database. J Thorac Cardiovasc Surg 137:82–90PubMedCrossRefGoogle Scholar
- 27.Regitz-Zagrosek V, Blomstrom Lundqvist CB, Borghi C et al (2011) ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC). Eur Heart J 32:3147–3197PubMedCrossRefGoogle Scholar