Preparation of gold nanoparticles via direct interaction of tetrachloroauric acid with DNA

  • Evgeny A. Karpushkin
  • Yury D. Aleksandrov
  • Anna V. Gibalova
  • Artem M. Abakumov
  • Larisa I. Lopatina
  • Vladimir G. Sergeyev
Invited Article


Reduction of chloroauric acid with DNA in neutral aqueous medium has been systematically studied by means of electron absorption spectroscopy and transmission electron microscopy. The reduction has afforded ultrasmall gold nanoparticles (diameter of 1 nm), which exhibit excellent stability and perfect catalytic properties in the model reaction of p-nitrophenol reduction.


Gold DNA Catalysis Nanoparticles Colloidal stability 



Authors are grateful to Mariia A. Lukianova for constructive criticism of the manuscript.

Funding information

This work was financially supported by the Russian Foundation for Basic Research (project no. 17-08-01087).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

396_2018_4448_MOESM1_ESM.docx (8.5 mb)
ESM 1 (DOCX 8747 kb)


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Chemistry DepartmentLomonosov Moscow State UniversityMoscowRussia
  2. 2.Skolkovo Institute of Science and TechnologyMoscowRussia

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