Colloid and Polymer Science

, Volume 290, Issue 16, pp 1609–1616 | Cite as

Effects of Hofmeister anions on the flocculation behavior of temperature-responsive poly(N-isopropylacrylamide) microgels

  • Shirin Fanaian
  • Nodar Al-Manasir
  • Kaizheng Zhu
  • Anna-Lena Kjøniksen
  • Bo NyströmEmail author
Original Contribution


Effects of some sodium salts (NaCl, NaClO3, and NaSCN) in the Hofmeister series on deswelling and temperature-induced aggregation behavior of microgels of poly(N-isopropylacrylamide) (PNIPAAM) and PNIPAAM-co-PAA with attached poly(acrylic acid) moieties were investigated with the aid of turbidimetry and dynamic light scattering. Addition of salt in the concentration range 0.1–0.5 M generated aggregation of the PNIPAAM microgel particles at elevated temperatures, but it was no distinct difference between chaotropic and kosmotropic anions. In contrast, the flocculation behavior at high temperatures for PNIPAAM-co-PAA revealed a prominent influence of salinity and type of anion on the formation of aggregates. The aggregation transition was shifted to the highest temperature for the most chaotropic anion (SCN), and the aggregation transition at the same salt concentration is consistent with the typical Hofmeister series. The turbidity results from the PNIPAAM-co-PAA microgels disclosed a two-step transition for the considered anions, and both a low and high temperature change in the turbidity data was observed. The high-temperature transition followed the Hofmeister series.


Temperature-responsive aggregation Microgels Salt effect Hofmeister series PNIPAAM Turbidimetry Dynamic light scattering 



We gratefully acknowledge the financial support from the Norwegian Research Council for the PETROMAKS project 30881/S60 and VISTA for the project 6506.


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Shirin Fanaian
    • 1
  • Nodar Al-Manasir
    • 1
  • Kaizheng Zhu
    • 1
  • Anna-Lena Kjøniksen
    • 1
    • 2
  • Bo Nyström
    • 1
    Email author
  1. 1.Department of ChemistryUniversity of OsloOsloNorway
  2. 2.Department of Pharmaceutics, School of PharmacyUniversity of OsloOsloNorway

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