Acute citrulline malate supplementation improves upper- and lower-body submaximal weightlifting exercise performance in resistance-trained females
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Citrulline malate (CM) is a nonessential amino acid that increases exercise performance in males. However, based on physiological differences between genders, these results cannot be extrapolated to females. Therefore, the purpose of this investigation was to evaluate effects of acute CM supplementation on upper- and lower-body weightlifting performance in resistance-trained females.
Fifteen females (23 ± 3 years) completed two randomized, double-blind trials consuming either CM (8 g dextrose + 8 g CM) or a placebo (8 g dextrose). One hour after supplement consumption, participants performed six sets each of upper- (i.e., bench press) and lower-body (i.e., leg press) exercises to failure at 80 % of previously established one-repetition maximum. Immediately after each set, repetitions completed, heart rate and rating of perceived exertion (RPE) were recorded.
Repeated-measures analysis of variance indicated that subjects completed significantly (p = .045) more repetitions throughout upper-body exercise when consuming CM versus placebo (34.1 ± 5.7 vs. 32.9 ± 6.0, respectively). When consuming CM, similar significant (p = .03) improvements in total repetitions completed were observed for lower-body exercise (66.7 ± 30.5 vs. 55.13 ± 20.64, respectively). Overall RPE score was significantly lower (p = .02) in upper-body exercise when subjects consumed CM versus placebo (7.9 ± 0.3 and 8.6 ± 0.2, respectively). The supplement consumed exhibited no significant effects on heart rate at any time point.
Acute CM supplementation in females increased upper- and lower-body resistance exercise performance and decreased RPE during upper-body exercise. These data indicate that athletes competing in sports with muscular endurance-based requirements may potentially improve performance by acutely supplementing CM.
KeywordsErgogenic aid Sports nutrition Amino acids Resistance exercise Women Nitric oxide
Funding for this investigation was provided by the Statewide Undergraduate Research Fellowship. The authors would like to thank Jarrion Lawson for his help with the dietary analysis and data collection portions of this project. We would also like to thank Shari Witherspoon for her assistance during the process of ordering and acquiring the necessary materials required throughout this investigation.
- 3.Coleman E (1998) Ergogenic aids for athletes. Clin Nutr Insight 24:1–4Google Scholar
- 10.United States Department of Commerce (2011) Age and sex composition: 2010, vol 1. U S Census Bureau, pp 1–16Google Scholar
- 11.Herbold NH, Visconti BK, Frates S, Bandini L (2004) Traditional and nontraditional supplement use by collegiate female varsity athletes. Int J Sport Nutr Exerc Metab 14:583–593Google Scholar
- 23.American College of Sports Medicine (2013) ACSM’s guidelines for exercise testing and prescription. Lippincott Williams & Wilkins, PhiladelphiaGoogle Scholar
- 24.Jurkowski J, Jones NL, Toews CJ, Sutton JR (1981) Effects of menstrual cycle on blood lactate, O2 delivery, and performance during exercise. J Appl Physiol 51:1493–1499Google Scholar
- 27.Glenn J, Gray M, Vincenzo J (2014) Differences in regional adiposity, bone mineral density, and physical exercise participation based on exercise self-efficacy among senior adults. J Sports Med Phys Fit 55(10):1166–1173Google Scholar
- 28.Baechle TR, Earle RW (2008) Essentials of strength training and conditioning. Human Kinetics, ChampaignGoogle Scholar
- 30.Lagally KM, Robertson RJ (2006) Construct validity of the OMNI resistance exercise scale. J Strength Cond Res 20:252–256Google Scholar
- 31.McGee KJ, Burkett LN (2003) The National Football League combine: a reliable predictor of draft status? J Strength Cond Res 17:6–11Google Scholar
- 35.Janssen I, Heymsfield SB, Wang ZM, Ross R (2000) Skeletal muscle mass and distribution in 468 men and women aged 18–88 yr. J Appl Physiol 89:81–88Google Scholar
- 37.Bloomer RJ, Farney TM, Trepanowski JF, McCarthy CG, Canale RE, Schilling BK (2010) Comparison of pre-workout nitric oxide stimulating dietary supplements on skeletal muscle oxygen saturation, blood nitrate/nitrite, lipid peroxidation, and upper body exercise performance in resistance trained men. J Int Soc Sports Nutr 7:1–15CrossRefGoogle Scholar
- 38.Hartman WJ, Torre PM, Prior RL (1994) Dietary citrulline but not ornithine counteracts dietary arginine deficiency in rats by increasing splanchnic release of citrulline. J Nutr 124:1950–1960Google Scholar
- 41.Walker JB (1979) Creatine: biosynthesis, regulation, and function. Adv Enzymol Relat Areas Mol Biol 50:177–242Google Scholar
- 42.Paddon-Jones D, Borsheim E, Wolfe RR (2004) Potential ergogenic effects of arginine and creatine supplementation. J Nutr 134:2888–2894Google Scholar