Treatment for vitamin D deficiency: here and there do not mean everywhere
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The optimal levels of vitamin D and the best treatment for vitamin D deficiency are the object of intense discussion. As for the threshold value of 25-hydroxyvitamin D (25(OH)D) defining a sufficient vitamin D status, a dedicated Committee of the Institute of Medicine recently stated that a serum concentration of at least 50 nmol/L meets the needs of at least 97.5% of the population [1, 2]. The corresponding recommended dietary allowance (RDA) in adults is 600 IU per day up to 70 years of age and 800 IU daily thereafter. Notably, these intakes are based on an assumption of minimal or no sun exposure. The IOM Committee’s members considered bone health as the only outcome consistently and causally linked to vitamin D and concluded that studies about the potential positive effects of vitamin D on calcium absorption and balance, physical performance, and risk of falls are still inconclusive as to causality. However, many experts deem the evidence that vitamin D supplementation improves...
KeywordsRickets Osteomalacia North Latitude Recommended Dietary Allowance Serum Parathyroid Hormone
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