Lifestyle and diet in people using dietary supplements
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The use of dietary supplements is often associated with a healthy lifestyle. Due to high variation in supplementation practice by country, these associations will be investigated in a large German cohort study.
Aim of the study
To describe the prevalence of dietary supplement use in the EPIC-Heidelberg cohort and to illuminate differences in health-relevant characteristics between regular users and non-users.
At cohort recruitment, 13,615 women aged 35–65 and 11,929 men aged 40–65 were asked for regular dietary supplementation over the past year.
Regular use of any supplement was reported by 47% of the women and 41% of the men, vitamin or mineral supplements were taken by 40% and 33%, respectively. The use of vitamin and/or mineral supplements was significantly associated with higher age, being non- or ex-smoker, lower BMI, higher physical leisure time activity, and higher educational level. After adjustment for these factors, we observed positive associations between supplement use and the consumption of milk, milk products, and fish as well as the intake of vitamin C and β-carotene. In contrast, the supplement use was related to lower meat and meat product consumption, saturated fat intake, and n6/n3-fatty acid ratio in the diet, both in women and men. Except for Hemoccult® testing in women, no association with participation in cancer screening was observed.
The high prevalence of supplement use in EPIC-Heidelberg was associated with several presumably healthier lifestyle and diet characteristics. This needs to be considered in further evaluations of the risk of chronic diseases.
Keywordsnutrient supplements vitamins diet lifestyle epidemiology
EPIC-Heidelberg is supported by the Deutsche Krebshilfe [Grant-No.:70-488-Ha I], Deutsches Krebsforschungszentrum, and the Program “Europe against Cancer” of the European Commission [Grant-No.:S12.296584 (2000CVG 2–014)].
- 7.Blair SN, Kohl HW, Gordon NF, Paffenbarger RS (1992) How much physical activity is good for health? Annu Rev Public Health 13:99–126Google Scholar
- 8.Block G, Cox C, Madans J, Schreiber GB, Licitra L, Melia N (1988) Vitamin supplement use, by demographic characteristics. Am J Epidemiol 127:297–309Google Scholar
- 9.Boeing H, Bohlscheid-Thomas S, Voss S, Schneeweiss S, Wahrendorf J (1997) The relative validity of vitamin intakes derived from a food frequency questionnaire compared to 24-hour recalls and biological measurements: results from the EPIC pilot study in Germany. European prospective investigation into cancer and nutrition. Int J Epidemiol 26(Suppl 1):S82–90CrossRefGoogle Scholar
- 12.Bohlscheid-Thomas S, Hoting I, Boeing H, Wahrendorf J (1997) Reproducibility and relative validity of energy and macronutrient intake of a food frequency questionnaire developed for the German part of the EPIC project. European prospective investigation into cancer and nutrition. Int J Epidemiol 26(Suppl 1):S71–81CrossRefGoogle Scholar
- 13.Bohlscheid-Thomas S, Hoting I, Boeing H, Wahrendorf J (1997) Reproducibility and relative validity of food group intake in a food frequency questionnaire developed for the German part of the EPIC project. European prospective investigation into cancer and nutrition. Int J Epidemiol 26(Suppl 1):S59–70CrossRefGoogle Scholar
- 15.Bundesfachverband der Arzneimittel-Hersteller e.V (2005) Der Arzneimittelmarkt in Deutschland in Zahlen 2004. Bundesfachverband der Arzneimittel-Hersteller e.V. Wissenschafts- und Wirtschaftsdienst, BonnGoogle Scholar
- 16.Frank E, Bendich A, Denniston M (2000) Use of vitamin-mineral supplements by female physicians in the United States. Am J Clin Nutr 72:969–975Google Scholar
- 17.Giovannucci E, Stampfer MJ, Colditz GA, et al. (1998) Multivitamin use, folate, and colon cancer in women in the nurses’ health study. Ann Intern Med 129:517–524Google Scholar
- 19.Joint WHO/FAO Expert Consultation on Diet Nutrition and the Prevention of Chronic Diseases (2002) Diet, nutrition and the prevention of chronic diseases: report of a joint WHO/FAO expert consultation. World Health Organization, GenevaGoogle Scholar
- 24.Lampe JW (1999) Health effects of vegetables and fruit: assessing mechanisms of action in human experimental studies. Am J Clin Nutr 70:475S–490SGoogle Scholar
- 26.Lyle BJ, Mares-Perlman JA, Klein BE, Klein R, Greger JL (1998) Supplement users differ from nonusers in demographic, lifestyle, dietary and health characteristics. J Nutr 128:2355–2362Google Scholar
- 28.McNaughton SA, Mishra GD, Paul AA, Prynne CJ, Wadsworth MEJ (2005) Supplement use is associated with health status and health-related behaviors in the 1946 British birth cohort. J Nutr 135:1782–1789Google Scholar
- 29.Mensink GB, Strobel A (1999) Intake of dietary supplements and nutritional behavior]. Gesundheitswesen 61(Spec No):S132–137Google Scholar
- 30.Miller ER III, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E (2004) Meta-analysis: high-dosage vitamin e supplementation may increase all-cause mortality. Ann Intern Med 142:37–46Google Scholar
- 34.Patterson R, Neuhouser M, White E, Hunt J, Kristal A (1998) Cancer-related behavior of vitamin supplement users. Cancer Epidemiol Biomarkers Prev 7:79–81Google Scholar
- 39.Statistisches Bundesamt (2000) Bildung im Zahlenspiegel 2000. Statistisches Bundesamt, WiesbadenGoogle Scholar
- 44.Wolters M, Hahn A (2001) [Nährstoffsupplemente aus Sicht des Konsumenten]. Ernährungs-Umschau 48:136–141Google Scholar