DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen
3 Klinische Symptomatik
Leitlinien
First Online:
- 202 Downloads
- 3 Citations
German Society for Rheumatology S3 guidelines on axial spondyloarthritis including Bechterew’s disease and early forms
3 Clinical symptoms
Notes
Einhaltung ethischer Richtlinien
Interessenkonflikt. U. Kiltz, M. Rudwaleit, J. Sieper, D. Krause, J.-F. Chenot, A. Stallmach, S. Jaresch, U. Oberschelp, E. Schneider, B. Swoboda,·H. Böhm, A. Heiligenhaus, U. Pleyer, W.-H. Böhncke, M. Stemmer und J. Braun geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren. This article is part of a supplement sponsored by AbbVie, Pfizer und UCB.
Literatur
- 1.Braun J, Sieper J (2007) Ankylosing spondylitis. Lancet 369(9570):1379–1390PubMedCrossRefGoogle Scholar
- 2.Rojas-Vargas M et al (2009) First signs and symptoms of spondyloarthritis – data from an inception cohort with a disease course of two years or less (REGISPONSER-Early). Rheumatology (Oxford) 48(4):404–409Google Scholar
- 3.Calin A et al (1977) Clinical history as a screening test for ankylosing spondylitis. JAMA 237(24):2613–2614PubMedCrossRefGoogle Scholar
- 4.Rudwaleit M et al (2006) Inflammatory back pain in ankylosing spondylitis: a reassessment of the clinical history for application as classification and diagnostic criteria. Arthritis Rheum 54(2):569–578PubMedCrossRefGoogle Scholar
- 5.Sieper J et al (2009) New criteria for inflammatory back pain in patients with chronic back pain: a real patient exercise by experts from the Assessment of SpondyloArthritis international Society (ASAS). Ann Rheum Dis 68(6):784–788PubMedCrossRefGoogle Scholar
- 6.Landewe R et al (2009) Physical function in ankylosing spondylitis is independently determined by both disease activity and radiographic damage of the spine. Ann Rheum Dis 68(6):863–867PubMedCrossRefGoogle Scholar
- 7.Machado P et al (2010) Both structural damage and inflammation of the spine contribute to impairment of spinal mobility in patients with ankylosing spondylitis. Ann Rheum Dis 69(8):1465–1470PubMedCrossRefGoogle Scholar
- 8.Ruta S et al (2011) Prevalence of subclinical enthesopathy in patients with spondyloarthropathy: an ultrasound study. J Clin Rheumatol 17(1):18–22PubMedCrossRefGoogle Scholar
- 9.Maksymowych WP et al (2009) Development and validation of the Spondyloarthritis Research Consortium of Canada (SPARCC) enthesitis index. Ann Rheum Dis 68(6):948–953PubMedCrossRefGoogle Scholar
- 10.Heuft-Dorenbosch L et al (2003) Assessment of enthesitis in ankylosing spondylitis. Ann Rheum Dis 62(2):127–132PubMedCentralPubMedCrossRefGoogle Scholar
- 11.Sidiropoulos PI et al (2008) Evidence-based recommendations for the management of ankylosing spondylitis: systematic literature search of the 3E Initiative in Rheumatology involving a broad panel of experts and practising rheumatologists. Rheumatology (Oxford) 47(3):355–361Google Scholar
- 12.Karberg K et al (2005) Bone loss is detected more frequently in patients with ankylosing spondylitis with syndesmophytes. J Rheumatol 32(7):1290–1298PubMedGoogle Scholar
- 13.Jun JB et al (2006) Femoral bone mineral density is associated with vertebral fractures in patients with ankylosing spondylitis: a cross-sectional study. J Rheumatol 33(8):1637–1641PubMedGoogle Scholar
- 14.Gratacos J et al (1999) Significant loss of bone mass in patients with early, active ankylosing spondylitis: a followup study. Arthritis Rheum 42(11):2319–2324PubMedCrossRefGoogle Scholar
- 15.Vosse D et al (2009) Ankylosing spondylitis and the risk of fracture: results from a large primary care-based nested case-control study. Ann Rheum Dis 68(12):1839–1842PubMedCrossRefGoogle Scholar
- 16.Montala N et al (2011) Prevalence of vertebral fractures by semiautomated morphometry in patients with ankylosing spondylitis. J Rheumatol 38(5):893–897PubMedCrossRefGoogle Scholar
- 17.Westerveld LA, Verlaan JJ, Oner FC (2009) Spinal fractures in patients with ankylosing spinal disorders: a systematic review of the literature on treatment, neurological status and complications. Eur Spine J 18(2):145–156PubMedCentralPubMedCrossRefGoogle Scholar
- 18.Haywood KL et al (2004) Spinal mobility in ankylosing spondylitis: reliability, validity and responsiveness. Rheumatology (Oxford) 43(6):750–757Google Scholar
- 19.Wanders A et al (2005) Association between radiographic damage of the spine and spinal mobility for individual patients with ankylosing spondylitis: can assessment of spinal mobility be a proxy for radiographic evaluation? Ann Rheum Dis 64(7):988–994PubMedCentralPubMedCrossRefGoogle Scholar
- 20.Heuft-Dorenbosch L et al (2004) Measurement of spinal mobility in ankylosing spondylitis: comparison of occiput-to-wall and tragus-to-wall distance. J Rheumatol 31(9):1779–1784PubMedGoogle Scholar
- 21.Deyo RA, Diehr P, Patrick DL (1991) Reproducibility and responsiveness of health status measures. Statistics and strategies for evaluation. Control Clin Trials 12(4 Suppl):142S–158SPubMedCrossRefGoogle Scholar
- 22.Pile KD et al (1991) Clinical assessment of ankylosing spondylitis: a study of observer variation in spinal measurements. Br J Rheumatol 30(1):29–34PubMedCrossRefGoogle Scholar
- 23.Gladman DD et al (2007) International spondyloarthritis interobserver reliability exercise – the INSPIRE study: I. Assessment of spinal measures. J Rheumatol 34(8):1733–1739PubMedGoogle Scholar
- 24.Kennedy LG et al (1995) Ankylosing spondylitis: the correlation between a new metrology score and radiology. Br J Rheumatol 34(8):767–770PubMedCrossRefGoogle Scholar
- 25.Chandran V et al (2007) Relationship between spinal mobility and radiographic damage in ankylosing spondylitis and psoriatic spondylitis: a comparative analysis. J Rheumatol 34(12):2463–2465PubMedGoogle Scholar
- 26.Jenkinson TR et al (1994) Defining spinal mobility in ankylosing spondylitis (AS). The Bath AS Metrology Index. J Rheumatol 21(9):1694–1698PubMedGoogle Scholar
- 27.Calin A et al (1994) A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumatol 21(12):2281–2285PubMedGoogle Scholar
- 28.Garrett S et al (1994) A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol 21(12):2286–2291PubMedGoogle Scholar
- 29.Ruof J, Sangha O, Stucki G (1999) Evaluation of a German version of the Bath Ankylosing Spondylitis Functional Index (BASFI) and Dougados Functional Index (D-FI). Z Rheumatol 58(4):218–225PubMedCrossRefGoogle Scholar
- 30.Boonen A et al (2009) Spinal radiographic changes in ankylosing spondylitis: association with clinical characteristics and functional outcome. J Rheumatol 36(6):1249–1255PubMedCrossRefGoogle Scholar
- 31.Ward MM et al (2005) Risk factors for functional limitations in patients with long-standing ankylosing spondylitis. Arthritis Rheum 53(5):710–717PubMedCentralPubMedCrossRefGoogle Scholar
- 32.Daltroy LH et al (1990) A modification of the Health Assessment Questionnaire for the spondyloarthropathies. J Rheumatol 17(7):946–950PubMedGoogle Scholar
- 33.Doward LC et al (2007) Translation and validation of non-English versions of the Ankylosing Spondylitis Quality of Life (ASQOL) questionnaire. Health Qual Life Outcomes 5:7PubMedCentralPubMedCrossRefGoogle Scholar
- 34.Vander Cruyssen B et al (2007) The epidemiology of ankylosing spondylitis and the commencement of anti-TNF therapy in daily rheumatology practice. Ann Rheum Dis 66(8):1072–1077CrossRefGoogle Scholar
- 35.Brophy S, Calin A (2001) Ankylosing spondylitis: interaction between genes, joints, age at onset, and disease expression. J Rheumatol 28(10):2283–2288PubMedGoogle Scholar
- 36.Rudwaleit M et al (2009) The early disease stage in axial spondylarthritis: results from the German Spondyloarthritis Inception Cohort. Arthritis Rheum 60(3):717–727PubMedCrossRefGoogle Scholar
- 37.Kiltz U et al (2012) Do patients with non-radiographic axial spondylarthritis differ from patients with ankylosing spondylitis? Arthritis Care Res (Hoboken) 64(9):1415–1422CrossRefGoogle Scholar
- 38.Collantes E et al (2007) Disease pattern of spondyloarthropathies in Spain: description of the first national registry (REGISPONSER) extended report. Rheumatology (Oxford) 46(8):1309–1315Google Scholar
- 39.Bremander A et al (2011) Population-based estimates of common comorbidities and cardiovascular disease in ankylosing spondylitis. Arthritis Care Res (Hoboken) 63(4):550–556CrossRefGoogle Scholar
- 40.Chorus AM et al (2003) Quality of life and work in patients with rheumatoid arthritis and ankylosing spondylitis of working age. Ann Rheum Dis 62(12):1178–1184PubMedCentralPubMedCrossRefGoogle Scholar
- 41.Zeboulon N, Dougados M, Gossec L (2008) Prevalence and characteristics of uveitis in the spondyloarthropathies: a systematic literature review. Ann Rheum Dis 67(7):955–959PubMedCrossRefGoogle Scholar
- 42.Rosenbaum JT (1992) Acute anterior uveitis and spondyloarthropathies. Rheum Dis Clin North Am 18(1):143–151PubMedGoogle Scholar
- 43.Accorinti M et al (2010) Clinical features and prognosis of HLA B27-associated acute anterior uveitis in an Italian patient population. Ocul Immunol Inflamm 18(2):91–96PubMedCrossRefGoogle Scholar
- 44.Munoz-Fernandez S et al (2003) Sulfasalazine reduces the number of flares of acute anterior uveitis over a one-year period. J Rheumatol 30(6):1277–1279PubMedGoogle Scholar
- 45.Benitez-Del-Castillo JM et al (2000) Sulfasalazine in the prevention of anterior uveitis associated with ankylosing spondylitis. Eye (Lond) 14(Pt 3A):340–343Google Scholar
- 46.Braun J et al (2005) Decreased incidence of anterior uveitis in patients with ankylosing spondylitis treated with the anti-tumor necrosis factor agents infliximab and etanercept. Arthritis Rheum 52(8):2447–2451PubMedCrossRefGoogle Scholar
- 47.Sieper J et al (2010) Analysis of uveitis rates across all etanercept ankylosing spondylitis clinical trials. Ann Rheum Dis 69(1):226–229PubMedCrossRefGoogle Scholar
- 48.Rudwaleit M et al (2009) Adalimumab effectively reduces the rate of anterior uveitis flares in patients with active ankylosing spondylitis: results of a prospective open-label study. Ann Rheum Dis 68(5):696–701PubMedCentralPubMedCrossRefGoogle Scholar
- 49.Mielants H et al (1996) Course of gut inflammation in spondylarthropathies and therapeutic consequences. Baillieres Clin Rheumatol 10(1):147–164PubMedCrossRefGoogle Scholar
- 50.Mielants H et al (1995) The evolution of spondyloarthropathies in relation to gut histology. III. Relation between gut and joint. J Rheumatol 22(12):2279–2284PubMedGoogle Scholar
- 51.D’Inca R et al (2009) Articular manifestations in inflammatory bowel disease patients: a prospective study. Dig Liver Dis 41(8):565–569CrossRefGoogle Scholar
- 52.Peeters H et al (2008) Clinical and genetic factors associated with sacroiliitis in Crohn’s disease. J Gastroenterol Hepatol 23(1):132–137PubMedGoogle Scholar
- 53.Vavricka SR et al (2011) Frequency and risk factors for extraintestinal manifestations in the Swiss inflammatory bowel disease cohort. Am J Gastroenterol 106(1):110–119PubMedCrossRefGoogle Scholar
- 54.El Miedany Y et al (2006) The gastrointestinal safety and effect on disease activity of etoricoxib, a selective cox-2 inhibitor in inflammatory bowel diseases. Am J Gastroenterol 101(2):311–317CrossRefGoogle Scholar
- 55.Hoffmann JC et al (2008) Clinical practice guideline on diagnosis and treatment of Crohn’s disease. Z Gastroenterol 46(9):1094–1146PubMedCrossRefGoogle Scholar
- 56.Braun J et al (2007) Differences in the incidence of flares or new onset of inflammatory bowel diseases in patients with ankylosing spondylitis exposed to therapy with anti-tumor necrosis factor alpha agents. Arthritis Rheum 57(4):639–647PubMedCrossRefGoogle Scholar
- 57.Marzo-Ortega H et al (2003) Efficacy of etanercept for treatment of Crohn’s related spondyloarthritis but not colitis. Ann Rheum Dis 62(1):74–76PubMedCentralPubMedCrossRefGoogle Scholar
- 58.Toussirot E et al (2011) Development of inflammatory bowel disease during anti-TNF-alpha therapy for inflammatory rheumatic disease. A nationwide series. Joint Bone SpineGoogle Scholar
- 59.Bergfeldt L et al (1982) Ankylosing spondylitis: an important cause of severe disturbances of the cardiac conduction system. Prevalence among 223 pacemaker-treated men. Am J Med 73(2):187–191PubMedCrossRefGoogle Scholar
- 60.O’Neill TW, Bresnihan B (1992) The heart in ankylosing spondylitis. Ann Rheum Dis 51(6):705–706CrossRefGoogle Scholar
- 61.Sampaio-Barros PD et al (2007) Pulmonary involvement in ankylosing spondylitis. Clin Rheumatol 26(2):225–230PubMedCrossRefGoogle Scholar
- 62.El Maghraoui A et al (2004) Lung findings on thoracic high-resolution computed tomography in patients with ankylosing spondylitis. Correlations with disease duration, clinical findings and pulmonary function testing. Clin Rheumatol 23(2):123–128CrossRefGoogle Scholar
- 63.Souza AS Jr et al (2004) Pulmonary abnormalities in ankylosing spondylitis: inspiratory and expiratory high-resolution CT findings in 17 patients. J Thorac Imaging 19(4):259–263PubMedCrossRefGoogle Scholar
- 64.Gratacos J et al (1997) Secondary amyloidosis in ankylosing spondylitis. A systematic survey of 137 patients using abdominal fat aspiration. J Rheumatol 24(5):912–915PubMedGoogle Scholar
- 65.Peters MJ et al (2004) Cardiovascular risk profile of patients with spondylarthropathies, particularly ankylosing spondylitis and psoriatic arthritis. Semin Arthritis Rheum 34(3):585–592PubMedCrossRefGoogle Scholar
- 66.Heeneman S, Daemen MJ (2007) Cardiovascular risks in spondyloarthritides. Curr Opin Rheumatol 19(4):358–362PubMedCrossRefGoogle Scholar
- 67.Choe JY et al (2008) No differences of carotid intima-media thickness between young patients with ankylosing spondylitis and healthy controls. Joint Bone Spine 75(5):548–553PubMedCrossRefGoogle Scholar
- 68.Gonzalez-Juanatey C et al (2009) The high prevalence of subclinical atherosclerosis in patients with ankylosing spondylitis without clinically evident cardiovascular disease. Medicine (Baltimore) 88(6):358–365Google Scholar
- 69.Peters MJ et al (2010) Signs of accelerated preclinical atherosclerosis in patients with ankylosing spondylitis. J Rheumatol 37(1):161–166PubMedCrossRefGoogle Scholar
- 70.Peters MJ et al (2010) Ankylosing spondylitis: a risk factor for myocardial infarction? Ann Rheum Dis 69(3):579–581PubMedCrossRefGoogle Scholar
- 71.Mathieu S et al (2011) Cardiovascular profile in ankylosing spondylitis: a systematic review and meta-analysis. Arthritis Care Res (Hoboken) 63(4):557–563CrossRefGoogle Scholar
- 72.Halm VP van et al (2006) Increased disease activity is associated with a deteriorated lipid profile in patients with ankylosing spondylitis. Ann Rheum Dis 65(11):1473–1477PubMedCentralPubMedCrossRefGoogle Scholar
- 73.Spanakis E et al (2006) Modest but sustained increase of serum high density lipoprotein cholesterol levels in patients with inflammatory arthritides treated with infliximab. J Rheumatol 33(12):2440–2446PubMedGoogle Scholar
- 74.Eijk IC van et al (2009) Improvement of lipid profile is accompanied by atheroprotective alterations in high-density lipoprotein composition upon tumor necrosis factor blockade: a prospective cohort study in ankylosing spondylitis. Arthritis Rheum 60(5):1324–1330PubMedCrossRefGoogle Scholar
- 75.Eijk IC van et al (2009) Microvascular function is impaired in ankylosing spondylitis and improves after tumour necrosis factor alpha blockade. Ann Rheum Dis 68(3):362–366PubMedCrossRefGoogle Scholar
- 76.Peters MJ et al (2010) EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis. Ann Rheum Dis 69(2):325–331PubMedCrossRefGoogle Scholar
- 77.Tubergen A van et al (2002) Assessment of fatigue in patients with ankylosing spondylitis: a psychometric analysis. Arthritis Rheum 47(1):8–16PubMedCrossRefGoogle Scholar
- 78.Jones SD et al (1996) Fatigue in ankylosing spondylitis: its prevalence and relationship to disease activity, sleep, and other factors. J Rheumatol 23(3):487–490PubMedGoogle Scholar
- 79.Dagfinrud H et al (2005) Fatigue in patients with ankylosing spondylitis: a comparison with the general population and associations with clinical and self-reported measures. Arthritis Rheum 53(1):5–11PubMedCrossRefGoogle Scholar
- 80.Zochling J, Braun J (2009) Mortality in rheumatoid arthritis and ankylosing spondylitis. Clin Exp Rheumatol 27(4 Suppl 55):S127–S130PubMedGoogle Scholar
- 81.Brown WM, Doll R (1965) Mortality from cancer and other causes after radiotherapy for ankylosing spondylitis. Br Med J 2(5474):1327–1332PubMedCentralPubMedCrossRefGoogle Scholar
- 82.Wick RR et al (2008) Increased risk of myeloid leukaemia in patients with ankylosing spondylitis following treatment with radium-224. Rheumatology (Oxford) 47(6):855–859Google Scholar
- 83.Bakland G, Gran JT, Nossent JC (2011) Increased mortality in ankylosing spondylitis is related to disease activity. Ann Rheum Dis 70(11):1921–1925PubMedCrossRefGoogle Scholar
- 84.Zink A, Minden K (2010) Entzündlich rheumatische Erkrankungen, Heft 49, In: R.-K.I. Berlin (Hrsg). Gesundheitsberichterstattung des BundesGoogle Scholar
Copyright information
© Springer-Verlag Berlin Heidelberg 2014