Zeitschrift für Rheumatologie

, Volume 73, Issue 8, pp 754–757 | Cite as

Diffuse soft tissue and vascular calcification in systemic lupus erythematosus with chronic kidney disease

  • F. Yıldız
  • B. Kelle
  • D.A. Taş
  • B. Kaya
  • E. Altun
  • E. Erken


The systemic disorder of mineral and bone metabolism which is related to chronic kidney disease (CKD) is called mineral and bone disorder (MBD). Calcifications related to CKD-MBD may occur in ophthalmic tissue, arterial walls, subcutaneous and periarticular soft tissues and organs. The vascular calcifications are the most important causes of mortality and morbidity in CKD. Here, we present a case of systemic lupus erythematosus with early and disseminated calcifications of vascular and periarticular soft tissues related to CKD-MBD.


Atherosclerosis Lupus nephritis Hyperphosphatemia Hypocalcemia Calciferols 

Diffuse Weichgewebe- und Gefäßkalzifikation bei systemischem Lupus erythematosus mit chronischer Nierenerkrankung


Die bei chronischer Nierenerkrankung (CKD, „chronic kidney disease“) auftretende systemische Störung des Mineral- und Knochenstoffwechsels wird als MBD („mineral and bone disorder“) bezeichnet. Verkalkungen im Zusammenhang mit CKD-MBD können in okulären Geweben, arteriellen Gefäßwänden, subkutanen und periartikulären Weichgeweben sowie in Organen entstehen. Die Gefäßverkalkungen sind die Hauptgründe für Morbidität und Mortalität bei CKD. Im Beitrag vorgestellt wird ein an systemischem Lupus erythematosus erkrankter Patient mit früher, disseminierter, CKD-MBD-bezogener Kalzifikation von Gefäßen und periartikulärem Weichgewebe.


Atherosklerose Lupusnephritis Hyperphosphatämie Hypokalzämie Calciferole 


Compliance with ethical guidelines

Conflict of interest. F. Yıldız, B. Kelle, D.A. Taş, B. Kaya, E. Altun, and E. Erken state that there are no conflicts of interest.

The accompanying manuscript does not include studies on humans or animals.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • F. Yıldız
    • 1
  • B. Kelle
    • 2
  • D.A. Taş
    • 1
  • B. Kaya
    • 3
  • E. Altun
    • 3
  • E. Erken
    • 1
  1. 1.Internal Medicine and Rheumatology, Department of Rheumatology-Immunology, Balcalı HospitalCukurova University Faculty of MedicineSarıçamTurkey
  2. 2.Department of Physical Medicine and RehabilitationCukurova University Faculty of MedicineAdanaTurkey
  3. 3.Department of NephrologyCukurova University Faculty of MedicineAdanaTurkey

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