Zeitschrift für Rheumatologie

, Volume 72, Issue 2, pp 163–165

Schmerzmessung am Tiermodell

Neues aus der Forschung

Pain measurement in animal models

Literatur

  1. 1.
    Kissin I (2010) The development of new analgesics over the past 50 years: a lack of real breakthrough drugs. Anesth Analg 110:780–789PubMedCrossRefGoogle Scholar
  2. 2.
    Woolf CJ (2010) Overcoming obstacles to developing new analgesics. Nat Med 16:1241–1247PubMedCrossRefGoogle Scholar
  3. 3.
    Berge OG (2011) Predictive validity of behavioural animal models for chronic pain. Br J Pharmacol 164:1195–1206PubMedCrossRefGoogle Scholar
  4. 4.
    Stein C, Küchler S (2012) Non-analgesic effects of opioids: peripheral opioid effects on inflammation and wound healing. Curr Pharm Des 18(37):6053–6069PubMedCrossRefGoogle Scholar
  5. 5.
    Holmdahl R, Lorentzen JC, Lu S et al (2001) Arthritis induced in rats with nonimmunogenic adjuvants as models for rheumatoid arthritis. Immunol Rev 184:184–202PubMedCrossRefGoogle Scholar
  6. 6.
    Satoh M, Reeves WH (1994) Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane. J Exp Med 180:2341–2346PubMedCrossRefGoogle Scholar
  7. 7.
    Hacquard-Bouder C, Ittah M, Breban M (2006) Animal models of HLA-B27-associated diseases: new outcomes. Joint Bone Spine 73:132–138PubMedCrossRefGoogle Scholar
  8. 8.
    Hargreaves K, Dubner R, Brown F et al (1988) A new and sensitive method for measuring thermal nociception in cutaneus hyperalgesia. Pain 32(1):77–88PubMedCrossRefGoogle Scholar
  9. 9.
    D’Amour FE, Smith DL (1941) A method for determining loss of pain sensation. J Pharmacol Exp Ther 72:74–79Google Scholar
  10. 10.
    Randall LO, Selitto JJ (1957) A method for measurement of analgesic activity on inflamed tissue. Arch Int Pharmacodyn Ther 111:409–419PubMedGoogle Scholar
  11. 11.
    Handwerker HO, Brune K (1987) Deutschsprachige Klassiker der Schmerzforschung – Classical German Contributions to Pain Research. Tagblatt-Druckerei KG, HassfurtGoogle Scholar
  12. 12.
    Hall C, Ballachey EL (1932) A study of the rat’s behavior in a field: a contribution to method in comparative psychology. Univ Calif Publ Psych 6:1–12Google Scholar
  13. 13.
    Schott E, Berge OG, Angeby-Moller K et al (1994) Weight bearing as an objective measure of arthritic pain in the rat. J Pharmacol Toxicol Methods 31:79–83PubMedCrossRefGoogle Scholar
  14. 14.
    Coulthard P, Pleuvry BJ, Brewster M et al (2002) Gait analysis as an objective measure in a chronic pain model. J Neurosci Methods 116:197–213PubMedCrossRefGoogle Scholar
  15. 15.
    Langford DJ, Bailey AL, Chanda ML et al (2010) Coding of facial expressions of pain in the laboratory mouse. Nat Methods 7:447–449PubMedCrossRefGoogle Scholar
  16. 16.
    Ekman P, Friesen WV (1978) Facial action coding system. Consulting Psychology Press, Palo Alto, CAGoogle Scholar
  17. 17.
    Colpaert FC, Tarayre JP, Alliaga M et al (2001) Opiate self-administration as a measure of chronic nociceptive pain in arthritic rats. Pain 91:33–45PubMedCrossRefGoogle Scholar
  18. 18.
    Borenstein D, Altman R, Bello A et al (2010) Report of the American College of Rheumatology Pain Management Task Force. Arthritis Care Res (Hoboken) 62:590–599Google Scholar
  19. 19.
    Caterina MJ (2008) On the thermoregulatory perils of TRPV1 antagonism. Pain 136:3–4PubMedCrossRefGoogle Scholar
  20. 20.
    FitzGerald GA (2003) COX-2 and beyond: approaches to prostaglandin inhibition in human disease. Nat Rev Drug Discov 2:879–890PubMedCrossRefGoogle Scholar
  21. 21.
    Elia N, Tramer MR (2012) Guidelines on adequate data reporting: use them! Eur J Anaesthesiol 29:457–459PubMedCrossRefGoogle Scholar
  22. 22.
    London AJ, Kimmelman J, Carlisle B (2012) Research ethics. Rethinking research ethics: the case of postmarketing trials. Science 336:544–545PubMedCrossRefGoogle Scholar
  23. 23.
    Drazen JM (2012) Transparency for clinical trials – the TEST Act. New Engl J Med 367:863–864PubMedCrossRefGoogle Scholar
  24. 24.
    Lo B (2010) Serving two masters – conflicts of interest in academic medicine. New Engl J Med 362:669–671PubMedCrossRefGoogle Scholar
  25. 25.
    Landefeld CS, Steinman MA (2009) The Neurontin legacy – marketing through misinformation and manipulation. New Engl J Med 360:103–106PubMedCrossRefGoogle Scholar
  26. 26.
    26. Stein C (2011) Knowledge transfer between research and practice. Anaesthesist 60:405PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Klinik für Anästhesiologie und operative IntensivmedizinCharité Campus Benjamin Franklin, Freie Universität BerlinBerlinDeutschland

Personalised recommendations