Clinical Research in Cardiology

, Volume 106, Issue 2, pp 162–163 | Cite as

Response to Prof. Dr. med. Gunther Wiesner, Prof. Dr. med. Peter Tassani-Prell, and Dr. Patrick Mayr

Deep sedation versus general anaesthesia in percutaneous edge-to-edge mitral valve reconstruction using the MitraClip system
  • Suzanne de WahaEmail author
  • Steffen Desch
  • Ingo Eitel
  • Holger Thiele
Letter to the Editors


We thank the authors for their thoughtful discussion of our analysis.

First, as stated in the limitation section of the manuscript, we agree that the difference of intensive care unit length of stay following deep sedation (DS) could theoretically be explained by differing post-interventional therapeutic strategies and clinical infrastructure as well as growing experience [1]. However, with the exception of mode of anaesthesia, individual decision makers in both hospitals were the same and thus treatment strategies as well as post-interventional management did likely not differ significantly between the two centres. We thus do not believe that the site of centre is an important influencing factor.

Second, we agree that the observation of non-differing length of hospital stay is of importance. However, as already discussed in the manuscript, this can be most likely explained by non-procedural post-interventional related factors, such as decongestion or mobilisation. Length of...


Aortic Valve Replacement Catheter Ablation Deep Sedation Transcatheter Aortic Valve Replacement Left Atrial Appendage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Suzanne de Waha
    • 1
    • 2
    Email author
  • Steffen Desch
    • 1
    • 2
  • Ingo Eitel
    • 1
    • 2
  • Holger Thiele
    • 1
    • 2
  1. 1.University Heart Centre Luebeck, Department of Cardiology/Angiology/Intensive Care MedicineUniversity Hospital Schleswig-HolsteinLuebeckGermany
  2. 2.German Centre for Cardiovascular Research (DZHK), Partner site Hamburg/Kiel/LuebeckLuebeckGermany

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