Clinical Research in Cardiology

, Volume 104, Issue 10, pp 908–910 | Cite as

Valve-in-valve Medtronic CoreValve implantation into a degenerated transapical Ventor Embracer aortic valve bioprosthesis

  • Florian Schlotter
  • Stephan Haussig
  • Gerhard Schuler
  • Axel Linke
Letter to the Editors


Since the advent of TAVI as an alternative treatment to surgical aortic valve replacement, implantation numbers have exceeded 100,000 heart valves [1]. Among those are some 100 Medtronic Engager™ (originally Ventor Embracer™) self-expanding transapical implants [2], specifically designed to omit potentially life-threatening coronary obstruction [3].

While TAVI has had a remarkable impact on the management of patients with severe aortic stenosis with satisfactory short-term results [4, 5], only limited data exist on the durability and valve performance in the long term.

Here, we present the case of a transfemoral 23 mm Medtronic CoreValve™ (CoV) bioprosthesis (Medtronic Inc., Minneapolis, USA) TAVI into a degenerated transapical Ventor Embracer™ (VeE) bioprosthesis (Ventor Technologies Ltd.) implanted 5 years previously (Fig.  1).


Aortic Valve Prosthetic Valve Aortic Valve Stenosis Aortic Valve Regurgitation Medtronic CoreValve 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Complaince with ethical standards

Conflict of interest

Dr. Linke is a consultant to Medtronic and St. Jude Medical. He received speaker honoraria from Edwards, Medtronic and St. Jude Medical and is a proctor for Medtronic, Edwards and St. Jude Medical. Prof. Schuler and Dr. Schlotter report no conflict of interest.

Supplementary material

392_2015_886_MOESM1_ESM.avi (2.8 mb)
Video 1 Release of the 23 mm Medtronic CoreValveTM (CoV) into the stenotic Ventor EmbracerTM (VeV) bioprosthesis (AVI 2876 kb)
392_2015_886_MOESM2_ESM.avi (1.8 mb)
Video 2 Balloon-dilatation of the CoV (AVI 1822 kb)
392_2015_886_MOESM3_ESM.avi (1.1 mb)
Video 3 Aortic bulb angiography after the CoV implantation into the VeV bioprosthesis (AVI 1078 kb)


  1. 1.
    Bax JJ, Delgado V, Bapat V, Baumgartner H, Collet JP, Erbel R, Hamm C, Kappetein AP, Leipsic J, Leon MB, MacCarthy P, Piazza N, Pibarot P, Roberts WC, Rodés-Cabau J, Serruys PW, Thomas M, Vahanian A, Webb J, Zamorano JL, Windecker S (2014) Open issues in transcatheter aortic valve implantation. Part 1: patient selection and treatment strategy for transcatheter aortic valve implantation. Eur Heart J 35(38):2627–2638CrossRefPubMedGoogle Scholar
  2. 2.
    Holzhey D, Linke A, Treede H, Baldus S, Bleiziffer S, Wagner A, Börgermann J, Scholtz W, Vanoverschelde JL, Falk V (2013) Intermediate Follow-Up Results From the Multicenter Engager European Pivotal Trial. Ann Thorac Surg 96:2095–2100CrossRefPubMedGoogle Scholar
  3. 3.
    Zahn R, Schiele R, Zeymer U, Bauer T, Lehmann A, Cornelius B, Sack FU (2013) Occlusion of the left main stem: a rare, but life-threatening complication of transcatheter aortic valve implantation with the Medtronic CoreValve™ prosthesis. Clin Res Cardiol 102(4):323–326CrossRefPubMedGoogle Scholar
  4. 4.
    Adams DH, Popma JJ, Reardon MJ, Yakubov SJ, Coselli JS, Deeb GM, Gleason TG, Buchbinder M, Hermiller J, Kleiman NS, Chetcuti S, Heiser J, Merhi W, Zorn G, Tadros P, Robinson N, Petrossian G, Hughes GC, Harrison JK, Conte J, Maini B, Mumtaz M, Chenoweth S, Oh JK (2014) Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis. N Engl J Med 370(19):1790–1798CrossRefPubMedGoogle Scholar
  5. 5.
    Linke A, Wenaweser P, Gerckens U, Tamburino C, Bosmans J, Bleiziffer S, Blackman D, Schafer U, Muller R, Sievert H, Sondergaard L, Klugmann S, Hoffmann R, Tchetche D, Colombo A, Legrand VM, Bedogni F, Leprince P, Schuler G, Mazzitelli D, Eftychiou C, Frerker C, Boekstegers P, Windecker S, Mohr F-W, Woitek F, Lange R, Bauernschmitt R, Brecker S (2014) Treatment of aortic stenosis with a self-expanding transcatheter valve: the International Multi-centre ADVANCE Study. Eur Heart J 35(38):2672–2684CrossRefPubMedGoogle Scholar
  6. 6.
    Kappetein AP, Head SJ, Genereux P, Piazza N, van Mieghem NM, Blackstone EH, Brott TG, Cohen DJ, Cutlip DE, van Es GA, Hahn RT, Kirtane AJ, Krucoff MW, Kodali S, Mack MJ, Mehran R, Rodes-Cabau J, Vranckx P, Webb JG, Windecker S, Serruys PW, Leon MB (2012) Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document. Eur Heart J 33:2403–2418CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Florian Schlotter
    • 1
  • Stephan Haussig
    • 1
  • Gerhard Schuler
    • 1
  • Axel Linke
    • 1
  1. 1.Department of Internal Medicine/Cardiology, Heart Center LeipzigUniversity of LeipzigLeipzigGermany

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