Clinical Research in Cardiology

, Volume 97, Issue 9, pp 623–627

Clinical, angiographic and cardiovascular magnetic resonance findings in consecutive patients with Takotsubo cardiomyopathy

  • Oliver Koeth
  • Bernd Mark
  • Andreas Kilkowski
  • Günter Layer
  • Bernd Cornelius
  • Kleopatra Kouraki
  • Timm Bauer
  • Ralf Zahn
  • Jochen Senges
  • Uwe Zeymer
ORIGINAL PAPER

DOI: 10.1007/s00392-008-0661-x

Cite this article as:
Koeth, O., Mark, B., Kilkowski, A. et al. Clin Res Cardiol (2008) 97: 623. doi:10.1007/s00392-008-0661-x

Abstract

Background

The aim was to assess clinical, angiographic and cardiovascular magnetic resonance (CMR) findings in patients with Takotsubo cardiomyopathy.

Methods

Between 2003 and 2007, 20 consecutive patients admitted to our hospital with suspected acute myocardial infarction and presenting with apical ballooning in the left ventricular (LV) angiogram in the absence of a significant coronary artery disease, were included in the study. Echocardiography and CMR was performed in all patients.

Results

The mean age of patients with Takotsubo cardiomyopathy was 62 ± 8 years (range 43–78 years). Eighteen (90%) were female. Clinical presentations included chest pain (95%) and cardiogenic shock (5%). The mean angiographic LV ejection fraction on admission was 45% ± 9% (range 26%–60%) and resolved rapidly in all cases. Mean time delay between presentation CMR was 2 ± 1 days (range 1–6 days). Mean ejection fraction was 51% ± 15% (range 25%–81%). While 19 (95%) patients showed no evidence of late enhancement or signs of myocarditis in the CMR, 1 (5%) patient who was resuscitated showed hyperenhancement confined to the apex.

Conclusion

In patients showing the clinical picture of an acute myocardial syndrome and angiographic picture of a TakoTsubo cardiomyopathy, CMR might be helpful in confirming the diagnosis through the exclusion of other causes for the acute LV dysfunction.

Keywords

TakoTsubo apical ballooning CMR angiography 

Abbreviations

CK

creatine kinase

LV

left ventricular

CMR

cardiovascular magnetic resonance

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Oliver Koeth
    • 1
    • 3
  • Bernd Mark
    • 1
  • Andreas Kilkowski
    • 1
  • Günter Layer
    • 2
  • Bernd Cornelius
    • 2
  • Kleopatra Kouraki
    • 1
  • Timm Bauer
    • 1
  • Ralf Zahn
    • 1
  • Jochen Senges
    • 1
  • Uwe Zeymer
    • 1
  1. 1.Department of CardiologyHerzzentrum LudwigshafenLudwigshafenGermany
  2. 2.Department of RadiologyHerzzentrum LudwigshafenLudwigshafenGermany
  3. 3.Department of CardiologyKlinikum LudwigshafenLudwigshafenGermany

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