Paradoxical coronary embolism causing non-ST segment elevation myocardial infarction in a case of pulmonary embolism
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Summary.
We describe the case of a 61-year-old woman who simultaneously suffered a pulmonary embolism and a myocardial infarction due to paradoxical coronary artery embolism. Transesophageal echocardiography with injection of agitated hydroxyethyl starch revealed a patent foramen ovale. Thrombophlebistis of the left saphenous vein with extension of thrombus into the femoral vein could be identified as the source of embolism. Paradoxical coronary embolism is an underrecognized cause of MI. Diagnosis is particularly difficult, when MI and PE coincide, because of the similarity in clinical signs and symptoms of both entities. A high level of clinical suspicion and echocardiography, especially if performed soon after presentation, can be the clue to early diagnosis of PDE
Key words
Paradoxical embolism pulmonary embolism coronary artery embolism patent foramen ovale deep vein thrombosisGleichzeitiges Auftreten von Lungenembolie und Nicht-ST-Elevationsinfarkt bei paradoxer Embolie
Zusammenfassung.
Wir berichten über eine 61-jährige Patientin, bei der es, bedingt durch eine paradoxe Embolie, zum zeitgleichen Auftreten einer Lungenembolie und eines akuten Myokardinfarktes kam. Mittels transösophagealer Echokardiographie mit Injektion von aufgeschäumter Hydroxyethylstärke konnte ein offenes Foramen ovale nachgewiesen werden. Als Emboliequelle fand sich eine Thrombophlebitis der Vena saphena magna mit Thrombuspropagation in die Vena femoralis. Paradoxe Koronararterienembolien sind eine seltene, aber häufig unerkannte Ursache eines akuten Myokardinfarktes. Gleichzeitiges Vorliegen einer Lungenembolie erschwert ihre Diagnose weiter, da sich Symptome und klinische Zeichen beider Erkrankungen ähneln. Besondere Aufmerksamkeit und eine frühzeitige Echokardiographie können entscheidende Hinweise zur frühen Diagnose liefern.
Schlüsselwörter
Paradoxe Embolie Lungenembolie Koronararterienembolie Offenes Foramen ovale Tiefe BeinvenenthrombosePreview
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References
- 1.Meier-Ewert HK, Labib SB, Schick EC, Gossman DE, Stix MS, Williamson CA (2003) Paradoxical embolism in the left main coronary artery: diagnosis by transesophageal echocardiography. Mayo Clin Proc 78(1):103–106PubMedGoogle Scholar
- 2.Johnson B (1951) Paradoxical embolism. J Clin Pathol 4:316PubMedGoogle Scholar
- 3.Prizel KR, Hutchins GM, Bulkley BH (1978) Coronary artery embolism and myocardial infarction. Ann Intern Med 88(2):155–161PubMedGoogle Scholar
- 4.Jungbluth A, Erbel R, Darius H et al (1988) Paradoxical coronary embolism: case report and review of the literature. Am Heart J 116(3):879–885CrossRefPubMedGoogle Scholar
- 5.Wachsman DE, Jacobs AK (2003) Paradoxical coronary embolism: a rare cause of acute myocardial infarction. Rev Cardiovasc Med 4(2):107–111PubMedGoogle Scholar
- 6.Ward R, Jones D, Haponik EF (1995) Paradoxical embolism. An underrecognized problem. Chest 108(2):549–558PubMedGoogle Scholar
- 7.Zuha R, Price T, Powles R, Treleaven J (2000) Paradoxical emboli after central venous catheter removal. Ann Oncol 11(7):885–886CrossRefPubMedGoogle Scholar
- 8.Vasiljevic JD, Abdulla AK (1990) Coronary embolism by metastatic choriocarcinoma of the uterus: an unusual cause of ischemic heart disease. Gynecol Oncol 38(2):289–292CrossRefPubMedGoogle Scholar
- 9.Uchida S, Yamamoto M, Masaoka Y, Mikouchi H, Nishizaki Y (1999) A case of acute pulmonary embolism and acute myocardial infarction with suspected paradoxical embolism after laparoscopic surgery. Heart Vessels 14(4):197–200PubMedGoogle Scholar
- 10.Schatz JW, Fischer JA, Lee RF, Lampe RM (1974) Paradoxic coronary embolism in a patient with mid-systolic click syndrome. Chest 66(5):587–590PubMedGoogle Scholar
- 11.Mirarchi FL, Hecker J, Kramer CM (2000) Pulmonary embolism complicated by patent foramen ovale and paradoxical embolization. J Emerg Med 19(1):27–30CrossRefPubMedGoogle Scholar
- 12.Mercereau D, Klinke WP (1988) Paradoxical coronary embolism associated with an unusual interatrial flap valve. Can J Cardiol 4(3):140–143PubMedGoogle Scholar
- 13.Manno BV Jr (2002) Paradoxical embolism to the left main coronary artery: visualization by transesophageal echocardiography. J Am Soc Echocardiogr 15(11):1417–1418PubMedGoogle Scholar
- 14.Bussani R, Pavletic N, Silvestri F (1999) Images in cardiology acute myocardial infarct from paradoxical embolism in a case of massive pulmonary thromboembolism. Heart 81(4):430PubMedGoogle Scholar
- 15.Gerber RS, Sherman CT, Sack JB, Perloff JK (1992) Isolated paradoxical embolus to the right coronary artery. Am J Cardiol 70(20):1633–1635CrossRefPubMedGoogle Scholar
- 16.Gersony DR, Kim SH, Di Tullio M, Fard A, Rabbani L, Homma S (2001) Acute myocardial infarction caused by paradoxical coronary embolization in a patient with a patent foramen ovale. JAm Soc Echocardiogr 14(12):1227–1229CrossRefGoogle Scholar
- 17.Islam MA, Khalighi K, Goldstein JE, Raso J (2000) Paradoxical embolism-report of a case involving four organ systems. J Emerg Med 19(1):31–34CrossRefPubMedGoogle Scholar
- 18.Lang I, Steurer G, Weissel M, Burghuber OC (1988) Recurrent paradoxical embolism complicating severe thromboembolic pulmonary hypertension. Eur Heart J 9(6):678–681Google Scholar
- 19.Lin OS, Zak FG (1982) Paradoxical bone marrow coronary embolism following cardiopulmonary resuscitation. Jama 248(1):33Google Scholar
- 20.Loscalzo J, Wachsman DE, Jacobs AK (1986) Paradoxical embolism: clinical presentation, diagnostic strategies, and therapeutic options. Am Heart J 112(1):141–145CrossRefPubMedGoogle Scholar
- 21.Bell WR, Simon TL, DeMets DL (1977) The clinical features of submassive and massive pulmonary emboli. Am J Med 62(3):355–360CrossRefPubMedGoogle Scholar
- 22.Konstantinides S, Geibel A, Olschewski M et al (2002) Importance of cardiac troponins I and T in risk stratification of patients with acute pulmonary embolism. Circulation 106(10):1263–1268CrossRefPubMedGoogle Scholar
- 23.Pruszczyk P, Bochowicz A, Torbicki A et al (2003) Cardiac troponin T monitoring identifies high-risk group of normotensive patients with acute pulmonary embolism. Chest 123(6):1947–1952CrossRefPubMedGoogle Scholar
- 24.Meyer T, Binder L, Hruska N, Luthe H, Buchwald AB (2000) Cardiac troponin I elevation in acute pulmonary embolism is associated with right ventricular dysfunction. J Am Coll Cardiol 36(5):1632–1636CrossRefPubMedGoogle Scholar
- 25.Giannitsis E, Muller-Bardorff M, Kurowski Vet al (2000) Independent prognostic value of cardiac troponin T in patients with confirmed pulmonary embolism. Circulation 102(2):211–217PubMedGoogle Scholar
- 26.Ferrari E, Imbert A, Chevalier T, Mihoubi A, Morand P, Baudouy M (1997) The ECG in pulmonary embolism. Predictive value of negative T waves in precordial leads-80 case reports. Chest 111(3):537–543PubMedGoogle Scholar
- 27.Falterman TJ, Martinez JA, Daberkow D, Weiss LD (2001) Pulmonary embolism with ST segment elevation in leads V1 to V4: case report and review of the literature regarding electrocardiographic changes in acute pulmonary embolism. J Emerg Med 21(3):255–261CrossRefPubMedGoogle Scholar
- 28.Guidelines on diagnosis and management of acute pulmonary embolism (2000) Task force on pulmonary embolism, european society of cardiology. Eur Heart J 21(16):1301–1336CrossRefPubMedGoogle Scholar
- 29.Kurzyna M, Torbicki A, Pruszczyk P et al (2002) Disturbed right ventricular ejection pattern as a new Doppler echocardiographic sign of acute pulmonary embolism. Am J Cardiol 90(5):507–511CrossRefPubMedGoogle Scholar
- 30.McConnell MV, Solomon SD, Rayan ME, Come PC, Goldhaber SZ, Lee RT (1996) Regional right ventricular dysfunction detected by echocardiography in acute pulmonary embolism. Am J Cardiol 78(4):469–473CrossRefPubMedGoogle Scholar
- 31.Abrams GA, Rose K, Fallon MB et al (1999) Hepatopulmonary syndrome and venous emboli causing intracerebral hemorrhages after liver transplantation: a case report. Transplantation 68(11):1809–1811CrossRefPubMedGoogle Scholar
- 32.Meier B, Lock JE (2003) Contemporary management of patent foramen ovale. Circulation 107(1):5–9CrossRefPubMedGoogle Scholar
- 33.Braun M, Gliech V, Boscheri A et al (2004) Transcatheter closure of patent foramen ovale (PFO) in patients with paradoxical embolism. Periprocedural safety and mid-term follow-up results of three different device occluder systems. Eur Heart J 25(5):424–430CrossRefPubMedGoogle Scholar
- 34.Skowasch D, Peuster M, Andrie R, Tiemann K, Luderitz B, Bauriedel G (2004) Transcatheter PFO closure with a prominent Eustachian valve. Z Kardiol 93(2):162–165CrossRefPubMedGoogle Scholar
- 35.Wu LA, Malouf JF, Dearani JA et al (2004) Patent foramen ovale in cryptogenic stroke: current understanding and management options. Arch Intern Med 164(9):950–956CrossRefPubMedGoogle Scholar
- 36.Ischinger TA, Kemkes B, Boosfeld C (2003) Partial malposition of PFO closure device: indication for elective surgical removal? Discussion of indications, procedural and anatomical aspects. Z Kardiol 92(2):188–192CrossRefPubMedGoogle Scholar