International Journal of Colorectal Disease

, Volume 34, Issue 11, pp 1925–1931 | Cite as

Preoperative factors associated with prolonged postoperative in-hospital length of stay in patients with Crohn’s disease undergoing intestinal resection or strictureplasty

  • Thien Vinh LuongEmail author
  • Sanne Dich Grandt
  • Ionut Negoi
  • Saulius Palubinskas
  • Alaa El-Hussuna
Original Article



To investigate factors that influence postoperative in-hospital length of stay (LOS) in patients with Crohn’s disease (CD) undergoing bowel surgery. Furthermore, the study aimed to evaluate LOS as a surrogate for postoperative outcome.


This is a multicentre retrospective cohort study. Inclusion criteria were adult patients with CD who underwent bowel surgery with either anastomosis or stricturoplasty. All timings of surgeries were included regardless of the method of access to the abdominal cavities. Patients with stoma were excluded. Demographic data, preoperative medications, previous operations for CD, preoperative sepsis, and operation were recorded. Primary outcome was LOS while secondary outcome variable was postoperative complications.


A total of 449 patients who underwent abdominal surgery for CD were included. Of the 449 patients, 265 were female (59%). Median age was 37 years (IQR = 20), median LOS was 7 days (IQR = 6). Patients with longer LOS had higher rates of re-laparotomy/re-laparoscopy (45/228 (19.7%) versus 9/219 (4.1%) p = 0.01). In multivariate analysis, age (OR = 1.024 [CI 95% 1.007–1.041], p = 0.005), preoperative intra-abdominal abscess (OR = 0.39 [CI 95% 0.185–0.821], p = 0.013), and previous laparotomy/laparoscopy (OR = 0.57 [CI 95% 0.334–0.918], p = 0.021) were associated with prolonged LOS. LOS correlated with postoperative complications after adjustment for age, gender, previous laparotomy/laparoscopy, and preoperative intra-abdominal abscesses (OR = 1.28 [CI 95% 1.199–1.366], p < 0.0001).


Age, preoperative intra-abdominal abscess, and previous laparotomy/laparoscopy significantly prolonged LOS. LOS correlated with postoperative complications and can therefore be used in epidemiological or register-based studies as a surrogate for postoperative outcome.


Crohn’s disease Length of postoperative stay in hospital Postoperative complications Inflammatory bowel disease Surgery 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The project approved by Danish data agency (DataTilsynet HVH-2013-046 / 02515).

Statement of informed consent

Not relevant to this retrospective study at the time of data collection.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Thien Vinh Luong
    • 1
    Email author
  • Sanne Dich Grandt
    • 2
  • Ionut Negoi
    • 3
  • Saulius Palubinskas
    • 2
  • Alaa El-Hussuna
    • 2
  1. 1.Department of Nuclear Medicine and PET-CentreAarhus University HospitalAarhus NDenmark
  2. 2.Department of SurgeryAalborg University HospitalAalborgDenmark
  3. 3.Department of Surgery, Emergency Hospital of BucharestCarol Davila University of Medicine and Pharmacy BucharestBucharestRomania

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