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What’s wrong with the status quo? Plenty

  • Stephen E. GoldstoneEmail author
  • Richard Hillman
  • Naomi Jay
  • on behalf of the International Anal Neoplasia Society
Letter to the Editor
  • 22 Downloads

Dear Editor:

The International Anal Neoplasia Society (www.iansociety.org) is composed of clinicians, scientists, and advocates committed to better understanding the pathogenesis, diagnosis, treatment, and prevention of anal neoplasia with the ultimate goal of preventing anal cancer [1]. We are always interested in new research that helps us with our mission and read with interest the paper by Tomassi et al. describing their results of anal cancer incidence in patients treated within the Kaiser Permanente Southern California healthcare system [2]. We believe a more appropriate title for this paper might be “What’s wrong with the status quo?”

The authors collected data on over 5 million patients who had a least 1 year of “active membership” in the system between January 2005 and December 2015. Patients were evaluated with visual “inspection of the perineum, digital rectal examination, and anoscopy at interval times ranging from 3 to12 months (shorter interval if symptomatic or...

Notes

References

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    IANS Mission statement. Available from: URL:https://iansociety.org. Accessed December 31, 2018
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    Tomassi MJ, Abbas MA, Klaristenfeld DD (2019) Expectant management surveillance for patients at risk for squamous cell carcinoma of the anus: a large US healthcare system experience. Int J Colorectal Dis 34(1):47–54.  https://doi.org/10.1007/s00384-018-3167-7
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    SEER Cancer Statistics Factsheets: Anal Cancer. Available from: URL: https://seer.cancer.gov/statfacts/html/anus.html. Accessed May 14, 2018
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    Cajas-Monson LC, Ramamoorthy SL, Cosman BC (2018) Expectant management of high-grade anal dysplasia in people with HIV: long-term results. Dis Colon Rectum 61:1357–1363Google Scholar
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    Colón-López V, Shiels MS, Machin M, Ortiz AP, Strickler H, Castle PE, Pfeiffer RM, Engels EA (2018) Anal cancer risk among people with HIV infection in the United States. J Clin Oncol 36:68–75CrossRefGoogle Scholar
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    Goldstone SE, Lensing SY, Stier EA, Darragh T, Lee JY, van Zante A, Jay N, Berry-Lawhorn JM, Cranston RD, Mitsuyasu R, Aboulafia D, Palefsky JM, Wilkin T (2018) A randomized clinical trial of infrared coagulation ablation versus active monitoring of intra-anal high-grade dysplasia in HIV-infected adults: an AIDS malignancy consortium trial. Clin Infect Dis.  https://doi.org/10.1093/cid/ciy615

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Stephen E. Goldstone
    • 1
    Email author
  • Richard Hillman
    • 2
  • Naomi Jay
    • 3
  • on behalf of the International Anal Neoplasia Society
  1. 1.Icahn School of Medicine at Mount SinaiNew YorkUSA
  2. 2.Dysplasia and Anal Cancer ServicesSt. Vincent’s HospitalDarlinghurstAustralia
  3. 3.UCSF ANCRE CenterMount Zion HospitalSan FraciscoUSA

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