International Journal of Colorectal Disease

, Volume 34, Issue 2, pp 353–354 | Cite as

“Mesentery-based surgery” to prevent surgical recurrence in Crohn’s disease: from basics to surgical practice

  • Roberto PeltriniEmail author
  • L. Bucci
Letter to the Editor

Dear Editor:

Surgery in Crohn’s Disease (CD) has always been based on the principle of limiting intestinal resection to the diseased tract as much as possible, thus saving precious centimeter of intestine for the patient. Traditionally, intestinal resection takes place by following the edge of digestive tube, keeping away from the vessels that go into the mesentery and the mesocolon, unlike cancer surgery which obliges the surgeon to respect the oncological principles.

Recent studies have recognized the mesentery as a single anatomical and structural unit with functional properties that plays a role in both physiological and pathological mechanisms [1]. In particular, JC Coffey highlights that the main morphological changes of the mesentery (those detected intraoperatively by the surgeon): fat wrapping (or creeping fat) and mesenteric thickening are correlated with mucosal ulceration and degree of disease severity and that the mucosal ulceration is always confined to the mesenteric...


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of General and Specialist SurgeryUniversity of Naples Federico IINaplesItaly

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