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International Journal of Colorectal Disease

, Volume 34, Issue 2, pp 277–283 | Cite as

Oncological outcome of surgical site infection after colorectal cancer surgery

  • Jung Wook Huh
  • Woo Yong LeeEmail author
  • Yoon Ah Park
  • Yong Beom Cho
  • Hee Cheol Kim
  • Seong Hyeon Yun
  • Ho-Kyung Chun
Original Article
  • 120 Downloads

Abstract

Background

This study evaluated the oncological outcome of surgical site infection (SSI) after colorectal cancer surgery.

Methods

A total of 3675 consecutive patients with colorectal cancer who underwent curative resection from January 2009 to December 2011 were analyzed. The prognostic significance of SSI was evaluated. Risk factors for SSI were also identified using multivariate regression analysis.

Results

Overall SSI rate was 9.6%, in which 5.5% was superficial or deep SSI and 4.1% was organ/space SSI. Incidence of SSI varied significantly with tumor location (P < 0.001): 7.1% in colon cancer and 14.0% in rectal cancer. With a median follow-up period of 49.8 months, the 5-year disease-free survival rates of patients without and with SSI were 87% and 83%, respectively (P = 0.018). SSI predicted disease-free survival in univariate analysis. However, SSI was not an independent predictor of survival in multivariate analysis. Body mass index, ASA score, preoperative WBC count, rectal tumor, open surgery, operation time, and transfusion during surgery were independent predictors of SSI.

Conclusion

SSI predicted disease-free survival in colorectal cancer patients following curative surgery. Patient’ demographics, tumor characteristics, and perioperative conditions were independently associated with an increased likelihood of SSI.

Keywords

Colorectal cancer Surgical site infection Survival 

Notes

Compliance with ethical standards

This project was reviewed and approved by the appropriate institutional review board.

Conflict of interest

The authors declare that they have no conflicts of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Departments of Surgery, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulSouth Korea
  2. 2.Department of Surgery, Kangbuk Samsung HospitalSungkyunkwan University School of MedicineSeoulSouth Korea

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