Prevalence and recurrence rate of perianal abscess—a population-based study, Sweden 1997–2009
- 410 Downloads
The aim of this study was to assess the impact of diabetes mellitus, Crohn’s disease, HIV/aids, and obesity on the prevalence and readmission rate of perianal abscess.
The study cohort was based on the Swedish National Patient Register and included all patients treated for perianal abscess in Sweden 1997–2009. The prevalence and risk for readmission were assessed in association with four comorbidity diagnoses: diabetes mellitus, Crohn’s disease, HIV, and/or AIDS and obesity.
A total of 18,877 patients were admitted during the study period including 11,138 men and 4557 women (2.4:1). Crohn’s disease, diabetes, and obesity were associated with a significantly higher prevalence of perianal abscess than an age- and gender-matched background population (p < 0.05). In univariate analysis, neither age nor gender had any significant impact on the risk for readmission. In a multivariate Cox proportional hazard analysis, Crohns disease was the only significant risk factor for readmission of perianal abscess.
Crohn’s disease, diabetes, and obesity increase the risk for perianal abscess. Of these, Crohn’s and HIV has an impact on readmission. The pathogenesis and the influence of diabetes and obesity need further research if we are to understand why these diseases increase the risk for perianal abscess but not its recurrence.
KeywordsPerianal abscess Prevalence Readmission Sweden Risk factor
The study was supported by a grant from the Olle Engqvist Research Foundation.
Karin Strigård and Karin Adamo contributed to the conception, design, and interpretation of data. Fredrik Brännström and Gabriel Sandblom contributed to the acquisition, analysis, and interpretation of data.
Compliance with ethical standards
The manuscript does not contain clinical studies or patient data. The study was approved by the ethics review board of Stockholm, Sweden, 2009/1787-31.
Conflict of interest
The authors declare that they have no competing interests.
- 1.Benign Anorectal Diseases (2006) Diagnosis with endoanal and endorectal ultrasound; redigerad av Giulio Aniello Santoro, Giuseppe Di Falco. Springer-Verlag Italia, TurinGoogle Scholar
- 6.Hamberger B, Kir HU (2009) Liber AB, 113 98 StockholmGoogle Scholar
- 12.Salazar R, Sola C, Maroto P, Tabernero JM, Brunet J, Verger G, Valenti V, Cancelas JA, Ojeda B, Mendoza L, Rodriguez M, Montesinos J, Lopez-Lopez JJ (1999) Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. Bone Marrow Transplant 23:27–33CrossRefPubMedGoogle Scholar
- 14.Schwandner O (2011) Obesity is a negative predictor of success after surgery for complex anal fistula. BMC Gastroenterol 11Google Scholar