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Long-term follow-up and development of diverticulitis in patients diagnosed with diverticulosis of the colon

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Abstract

Introduction

Diverticulosis of the colon is the most occurring abnormality in the digestive tract. Little is known on the risk of developing diverticulitis.

Aim

The study aims to assess the risk of diverticulitis.

Patients and methods

All patients undergoing colonoscopy in the years 1998, 1999, and 2000 were studied. Patients with cancer, inflammatory bowel disease, anastomoses, and prior diverticulitis were excluded. In the summer of 2015, all hospital records, endoscopy reports, and reports from the department of radiology were studied. Diverticulitis had to be confirmed by the clinical presentation but also via ultrasound or CT scan. In order to obtain enough follow-up years, patients above the age of 75 years were excluded.

Results

After exclusions, a study group of 433 patients remained. There was no difference is gender between patients developing diverticulitis and those who did not. There was no difference in age at time of the index colonoscopy. The sum of follow-up years was 6191. Range of follow-up was 0 to 17 years. The mean follow-up was 14.1 years per patient. Thirty cases of diverticulitis (7 %) could be identified; this is 4.8 cases per 1000 years. The mean time to development of diverticulitis was 5.9 years. Diverticulitis had a mild presentation in 19 patients and a severe presentation needing surgical intervention in 11.

Conclusion

The risk of developing diverticulitis is low. This contradicts the belief that diverticulosis has a high rate of progression. These results can help inform patients with diverticulosis about their risk of developing acute diverticulitis.

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References

  1. Painter NS, Burkitt DP (1971) Diverticular disease of the colon. A deficiency disease of Western civilisation. BMJ 2:450–454

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  2. Cheskin LJ, Lampert RD (1995) Diverticular disease. Epidemiology and pharmacological treatment. Drugs Aging 6:55–63

    Article  PubMed  CAS  Google Scholar 

  3. Sheth AA, Longo W, Floch MH (2008) Diverticular disease and diverticulitis. Am J Gastroenterol 103:1550–1556

    Article  PubMed  Google Scholar 

  4. Mimura T, Bateman AC, Lee RL, Johnson PA, McDonald PJ, Talbot IC, Kamm MA, MacDonald TT, Pender SL (2004) Up-regulation of collagen and tissue inhibitors of matrix metalloproteinase in colonic diverticular disease. Dis Colon Rectum 47:371–378

    Article  PubMed  Google Scholar 

  5. Horner JL (1952) A study of diverticulitis of the colon in office practice. Gastroenterology 21:223–229

    PubMed  CAS  Google Scholar 

  6. Kubo A, Kagaya T, Nakagawa H (1985) Studies on complications of diverticular disease of the colon. Jpn J Med 24:39–43

    Article  PubMed  CAS  Google Scholar 

  7. Loffeld RJ, Van der Putten AB (2002) Diverticular disease of the colon and concomitant abnormalities in patients undergoing endoscopic evaluation of the large bowel. Color Dis 4:189–192

    Article  Google Scholar 

  8. Loffeld RJ, van der Putten AB (2002) Newly developing diverticular disease of the colon in patients undergoing repeated endoscopic evaluation. J Clin Gastroenterol 35:205–206

    Article  PubMed  CAS  Google Scholar 

  9. Shahedi K, Fuller G, Bolus R, Cohen E, Vu M, Shah R, Agarwal N, Kaneshiro M, Atia M, Sheen V, Kurzbard N, van Oijen MG, Yen L, Hodgkins P, Erder MH, Spiegel B (2013) Long-term risk of acute diverticulitis among patients with incidental diverticulosis found during colonoscopy. Clin Gastroenterol Hepatol 11:1609–1613

    Article  PubMed  Google Scholar 

  10. Oomen JL, Engel AF, Cuesta MA (2006) Mortality after acute surgery for complications of diverticular disease of the sigmoid colon is almost exclusively due to patient related factors. Color Dis 8:112–119

    Article  CAS  Google Scholar 

  11. Henneman D, van Bommel AC, Snijders A, Snijders HS, Tollenaar RA, Wouters MW, Fiocco M (2014) Ranking and rankability of hospital postoperative mortality rates in colorectal cancer surgery. Ann Surg 259:844–849

    Article  PubMed  Google Scholar 

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Correspondence to R. J. L. F. Loffeld.

Additional information

What this paper adds: This study shows that the risk of developing diverticulitis is rather low. This is reassuring for patients diagnosed with this condition.

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Loffeld, R.J.L.F. Long-term follow-up and development of diverticulitis in patients diagnosed with diverticulosis of the colon. Int J Colorectal Dis 31, 15–17 (2016). https://doi.org/10.1007/s00384-015-2397-1

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  • DOI: https://doi.org/10.1007/s00384-015-2397-1

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