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Synchronous gastric cancer in primary sporadic colorectal cancer patients in Korea

  • S. B. Lim
  • S. Y. Jeong
  • H. S. Choi
  • D. K. Sohn
  • C. W. Hong
  • K. H. Jung
  • H. J. Chang
  • J. G. ParkEmail author
  • I. J. Choi
  • C. G. Kim
Original Article

Abstract

Background and aims

Colorectal cancer has been reported to be the malignancy most frequently associated with gastric cancer in Korea. The aim of this study was to define the frequency and clinical characteristics of synchronous gastric cancer detected at preoperative esophagogastroduodenoscopy (EGD) in colorectal cancer patients.

Materials and methods

This prospective study analyzed the EGD results from 1,542 consecutive colorectal cancer patients who underwent surgery from January 2003 to December 2005 at the Center for Colorectal Cancer, National Cancer Center, Korea.

Results

Of the 1,542 cases, 1,155 (74.9%) underwent EGD at our center and 387 underwent EGD at other hospitals within 6 months before surgery. Of the 1,542 cases, synchronous gastric cancers were detected in 31 cases (2.0%). Of these 31 cases, 26 had early gastric cancer (EGC; 83.9%) and 5 had advanced gastric cancer. Ten (38.5%) of the 26 EGC cases were managed using endoscopic mucosal resection. Compared to colorectal cancer patients without synchronous gastric cancer, the group of patients with synchronous gastric cancer was older (65.5 ± 9.6 vs 58.4 ± 11.3 years, p = 0.001) and had a greater proportion of males (77.4 vs 59.4%, p = 0.043).

Conclusion

This study found that 2% of Korean sporadic colorectal cancer patients had synchronous gastric cancer. A preoperative EGD for colorectal cancer patients is likely to greatly assist in the diagnosis of synchronous gastric cancer at an early stage and the implementation of appropriate minimally invasive treatment.

Keywords

Synchronous gastric cancer Sporadic colorectal cancer Multiple primary neoplasm 

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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • S. B. Lim
    • 1
  • S. Y. Jeong
    • 1
  • H. S. Choi
    • 1
  • D. K. Sohn
    • 1
  • C. W. Hong
    • 1
  • K. H. Jung
    • 1
  • H. J. Chang
    • 1
  • J. G. Park
    • 1
    • 3
    Email author
  • I. J. Choi
    • 2
  • C. G. Kim
    • 2
  1. 1.Center for Colorectal Cancer, Research Institute and HospitalNational Cancer CenterGoyang-siKorea
  2. 2.Center for Gastric CancerResearch Institute and Hospital, National Cancer CenterGoyang-siKorea
  3. 3.Cancer Research Institute and Cancer Research CenterSeoul National UniversitySeoulKorea

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