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Primary spontaneous pneumothorax in children: factors predicting recurrence and contralateral occurrence

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Abstract

Background

The risk factors for recurrence in primary spontaneous pneumothorax (PSP) in children are not well known. We aimed to identify possible risk factors, and to evaluate the utility of computerised tomography (CT) scans in predicting future episodes.

Methods

We reviewed children aged < 18 years admitted to our institution for PSP from 2008 to 2017, excluding those with malignancies. Basic demographic data were extracted. Clinical data collected include pneumothorax laterality, CT results, treatment protocols and recurrences.

Results

63 patients were included, 19 (30.2%) of whom had CT scans. A total of 41 surgeries were performed. The median (interquartile range) age was 15.4 years (14.9–15.9), and body-mass index was 17.9 kg/m2 (15.8–19.3). 56 (88.9%) patients were male. Median follow-up duration was 19.8 months (11.6–35.9). Multivariate logistic regression analyses identified surgery in the first episode as a predictor for a subsequent contralateral occurrence (odds ratio [95% confidence interval] 32.026 [1.685–608.518], p = 0.021). No predictors for ipsilateral recurrence were found. CT scans were 76.5% sensitive for bleb detection, and predicted poorly for occurrence (positive predictive value 14.3%, likelihood ratio 1.1).

Conclusion

This is the first study demonstrating that surgery at first presentation appears to predict for occurrence of PSP on the contralateral lung. CT appears to be ineffective in detecting blebs and predicting PSP occurrence.

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Funding

No funding was received for this study.

Author information

Correspondence to Lin Yin Ong.

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Conflict of interest

All authors declare that they have no conflict of interest.

Ethical approval

Prior to data collection in this retrospective audit, ethical approval was obtained from SingHealth Centralised Institutional Review Board (IRB reference number 2016/2454).

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Ng, G.Y.H., Nah, S.A., Teoh, O.H. et al. Primary spontaneous pneumothorax in children: factors predicting recurrence and contralateral occurrence. Pediatr Surg Int 36, 383–389 (2020). https://doi.org/10.1007/s00383-020-04619-x

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