The effects of tobacco consumption on paternity rates of adults with a history of cryptorchidism
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To determine the effect of tobacco consumption on paternity rates in men with a history of cryptorchidism. To compare the paternity rates between formerly unilateral, bilateral cryptorchid smokers, and nonsmokers.
A retrospective cohort study of 153 men who had undergone orchiopexy between 1961 and 1985 at the Miguel Servet University Hospital (116 unilateral and 37 bilateral) and a control group of 100 men were evaluated by review of medical records and a questionnaire.
A total of 197 men filled the questionnaire (76.7%). There was no difference in paternity rates between smokers compared to nonsmokers (P = 0.21). In the unilateral cryptorchid men (ULC) group, there is no difference in paternity rates when compared with the controls (P = 0.079) or when comparing ULC smokers to ULC nonsmokers (P = 0.35). In the bilateral cryptorchid men (BLC) group, there is no difference in paternity rates when compared to controls (P = 0.075) or when comparing BLC smokers to BLC nonsmokers (P = 0.36). When comparing according to consumption, there is no difference between mild, moderate or heavy smoker cases and controls.
There is no difference in paternity rates between men with a history of cryptorchidism that consume tobacco compared to nonsmokers or controls. More studies are needed to determine the impact of tobacco consumption in formerly cryptorchid men.
KeywordsCryptorchidism Tobacco Paternity Fertility
All the authors contributed to the study conception and design. Material preparation and data collection were performed by Dr. RF, Dr. EC and Dr. BE. Analysis was performed by Dr. NÁ, Dr. ASH and Dr. PB. The first draft of the manuscript was written by Dr. RF and all the authors commented on previous versions of the manuscript. All the authors read and approved the final manuscript. The study was supervised by Dr. JG.
Compliance with ethical standards
Conflict of interest
The authors declare they have no conflicts of interest.
Research involving human participants
This retrospective study was approved by the Aragonese Institute of Health Sciences and approved by the ethical committee for research of the autonomous community of Aragon (CEICA) N°CP12/2014.
Informed consent was obtained from all individual participants included in the study.
- 19.Nizard J (2005) What are the epidemiological data on maternal and paternal smoking? J Gynecol Obstet Biol Reprod 34 Spec No 1:3S347–52Google Scholar