Pediatric Surgery International

, Volume 32, Issue 9, pp 845–850 | Cite as

Contraindications and image-defined risk factors in laparoscopic resection of abdominal neuroblastoma

  • Yujiro TanakaEmail author
  • Hiroshi Kawashima
  • Makiko Mori
  • Michimasa Fujiogi
  • Keisuke Suzuki
  • Hizuru Amano
  • Kaori Morita
  • Yuki Arakawa
  • Katsuyoshi Koh
  • Eiji Oguma
  • Tadashi Iwanaka
  • Hiroo Uchida
Original Article



Minimally invasive surgery (MIS) has become widely accepted as a technique for abdominal neuroblastoma resection. However, the indications for MIS are still controversial. The aim of this study was to evaluate image-defined risk factors (IDRFs), complications, and oncologic outcomes in patients with abdominal neuroblastomas treated with MIS.


Between August 1998 and February 2016, MIS was planned for 20 children with abdominal neuroblastomas. Clinical data were retrospectively reviewed and compared between the IDRF-negative and IDRF-positive patients.


On the basis of the latest IDRF guidelines, five patients were classified as IDRF-positive and four of them had operative complications; namely, partial infarction of the ipsilateral kidney or open conversion. Concerning the two patients who needed open conversion, the primary reason for open conversion was difficulty in dissection of the tumor from the vena cava. Preoperative images of these cases showed either deformation or subtotal encasement of the vena cava. Relapse occurred in three high-risk patients and in none of the low/intermediate-risk patients. No complication occurred in the IDRF-negative cases.


IDRF-negative might be a good indication for MIS for abdominal neuroblastoma. However, deformation or subtotal encasement of the vena cava should be considered as IDRF-positive for MIS.


Laparoscopy Neuroblastoma IDRF Vena cava 


Compliance with ethical considerations

Conflict of interest

No competing financial interests exist.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Yujiro Tanaka
    • 1
    Email author
  • Hiroshi Kawashima
    • 1
  • Makiko Mori
    • 2
  • Michimasa Fujiogi
    • 1
  • Keisuke Suzuki
    • 1
  • Hizuru Amano
    • 1
  • Kaori Morita
    • 1
  • Yuki Arakawa
    • 2
  • Katsuyoshi Koh
    • 2
  • Eiji Oguma
    • 3
  • Tadashi Iwanaka
    • 1
  • Hiroo Uchida
    • 4
  1. 1.Department of Pediatric SurgerySaitama Children’s Medical CenterSaitamaJapan
  2. 2.Department of Hematology/OncologySaitama Children’s Medical CenterSaitamaJapan
  3. 3.Department of RadiologySaitama Children’s Medical CenterSaitamaJapan
  4. 4.Department of Pediatric SurgeryNagoya University Graduate School of MedicineNagoyaJapan

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