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Pediatric Surgery International

, Volume 27, Issue 8, pp 805–809 | Cite as

Octreotide in the treatment of neonatal postoperative chylothorax: report of three cases and literature review

  • João Moreira-Pinto
  • Paula Rocha
  • Angélica Osório
  • Berta Bonet
  • Fátima Carvalho
  • Carlos Duarte
  • Luísa Oliveira
Review Article

Abstract

Chylothorax is a well-recognized complication after neonatal cardiothoracic surgery. Management strategies include cessation of enteral feedings, repeated aspiration, chest drainage, and total parenteral nutrition. Somatostatin and its analogue, octreotide, have been used with promising results. The authors present three cases of neonatal postoperative chylothorax in which octreotide was used. After literature review, we can say that octreotide is relatively safe, and may reduce clinical course and complications associated with neonatal postoperative chylothorax. One should be aware of possible association between octreotide and necrotizing enterocolitis. Prospective controlled trials supporting octreotide use are lacking.

Keywords

Chylothorax Newborn Congenital heart disease Congenital diaphragmatic hernia Esophageal atresia Octreotide 

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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • João Moreira-Pinto
    • 1
    • 3
  • Paula Rocha
    • 2
  • Angélica Osório
    • 1
  • Berta Bonet
    • 1
  • Fátima Carvalho
    • 1
  • Carlos Duarte
    • 2
  • Luísa Oliveira
    • 1
  1. 1.Serviço de Cirurgia PediátricaCentro Hospitalar do PortoPortoPortugal
  2. 2.Pediatric and Neonatal Intensive Care UnitCentro Hospitalar do PortoPortoPortugal
  3. 3.Life and Health Sciences Research InstituteUniversity of MinhoBragaPortugal

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