Pediatric Surgery International

, Volume 26, Issue 7, pp 753–757 | Cite as

Ciliated hepatic foregut cysts in children

  • Victor Zaydfudim
  • Michael J. Rosen
  • Lynette A. Gillis
  • Hernan Correa
  • Harold N. Lovvorn III
  • C. Wright Pinson
  • Burnett S. KellyJr.
Case Report


Ciliated hepatic foregut cyst (CHFC) is a rare foregut developmental malformation usually diagnosed in adulthood; however, rare cases have been reported in the pediatric population. CHFC can transform into a squamous cell carcinoma resulting in death despite surgical resection of the isolated malignancy. We report the presentation, evaluation, and surgical management of a symptomatic 17-year-old girl found to have a 6.5 × 4.5 cm CHFC and suggest that all patients with suspected CHFC undergo prompt evaluation and complete cyst excision.


Hepatic cyst excision Liver cyst Pediatric surgery Ciliated cyst 



We would like to thank Aaron Shaver, MD (Department of Pathology) for providing the histopathology photographs. This study was supported in part by the National Research Service Award T32HS013833 (VZ) from the Agency of Healthcare Research and Quality, and by the National Institute of Diabetes and Digestive and Kidney Disease Training Grant 2T32DK007673-13 (MR); both from the National Institutes of Health and US Department of Health and Human Services.


  1. 1.
    Wheeler DA, Edmondson HA (1984) Ciliated hepatic foregut cyst. Am J Surg Pathol 8:467–470CrossRefPubMedGoogle Scholar
  2. 2.
    Sharma S, Corn A, Kohli V, Wright HI, Sebastian A, Jabbour N (2008) Ciliated hepatic foregut cyst: an increasingly diagnosed condition. Dig Dis Sci 53:2818–2821CrossRefPubMedGoogle Scholar
  3. 3.
    Stringer MD, Jones MO, Woodley H, Wyatt J (2006) Ciliated hepatic foregut cyst. J Pediatr Surg 41:1180–1183CrossRefPubMedGoogle Scholar
  4. 4.
    Harty MP, Hebra A, Ruchelli ED, Schnaufer L (1998) Ciliated hepatic foregut cyst causing portal hypertension in an adolescent. AJR Am J Roentgenol 170:688–690PubMedGoogle Scholar
  5. 5.
    Vick DJ, Goodman ZD, Deavers MT, Cain J, Ishak KG (1999) Ciliated hepatic foregut cyst: a study of six cases and review of the literature. Am J Surg Pathol 23:671–677CrossRefPubMedGoogle Scholar
  6. 6.
    Betalli P, Gobbi D, Talenti E, Alaggio R, Gamba P, Zanon GF (2008) Ciliated hepatic foregut cyst: from antenatal diagnosis to surgery. Pediatr Radiol 38:230–232CrossRefPubMedGoogle Scholar
  7. 7.
    Kim S, White FV, McAlister W, Shepherd R, Mychaliska G (2005) Ciliated hepatic foregut cyst in a young child. J Pediatr Surg 40:e51–e53CrossRefPubMedGoogle Scholar
  8. 8.
    Carnicer J, Duran C, Donoso L, Saez A, Lopez A (1996) Ciliated hepatic foregut cyst. J Pediatr Gastroenterol Nutr 23:191–193CrossRefPubMedGoogle Scholar
  9. 9.
    Young AS, Nicol KK, Teich S, Ii WE (2007) Catheter-based drainage and agitation for definitive cytological diagnosis of a ciliated hepatic foregut cyst in a child. Pediatr Dev Pathol 10:153–156CrossRefPubMedGoogle Scholar
  10. 10.
    Vick DJ, Goodman ZD, Ishak KG (1999) Squamous cell carcinoma arising in a ciliated hepatic foregut cyst. Arch Pathol Lab Med 123:1115–1117PubMedGoogle Scholar
  11. 11.
    Furlanetto A, Dei Tos AP (2002) Squamous cell carcinoma arising in a ciliated hepatic foregut cyst. Virchows Arch 441:296–298CrossRefPubMedGoogle Scholar
  12. 12.
    de Lajarte-Thirouard AS, Rioux-Leclercq N, Boudjema K, Gandon Y, Ramee MP, Turlin B (2002) Squamous cell carcinoma arising in a hepatic foregut cyst. Pathol Res Pract 198:697–700CrossRefPubMedGoogle Scholar
  13. 13.
    Rogers TN, Woodley H, Ramsden W, Wyatt JI, Stringer MD (2007) Solitary liver cysts in children: not always so simple. J Pediatr Surg 42:333–339CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Victor Zaydfudim
    • 1
  • Michael J. Rosen
    • 2
  • Lynette A. Gillis
    • 2
  • Hernan Correa
    • 3
  • Harold N. Lovvorn III
    • 1
  • C. Wright Pinson
    • 1
  • Burnett S. KellyJr.
    • 1
    • 4
  1. 1.Department of SurgeryMonroe Carell Jr. Children’s Hospital at Vanderbilt UniversityNashvilleUSA
  2. 2.Division of Pediatric Gastroenterology, Hepatology and NutritionMonroe Carell Jr. Children’s Hospital at Vanderbilt UniversityNashvilleUSA
  3. 3.Department of PathologyMonroe Carell Jr. Children’s Hospital at Vanderbilt UniversityNashvilleUSA
  4. 4.Division of Hepatobiliary Surgery and Liver TransplantVanderbilt University Medical CenterNashvilleUSA

Personalised recommendations