Pediatric Surgery International

, Volume 24, Issue 8, pp 953–955 | Cite as

Dumbbell-shaped Ewing’s sarcoma family of tumor of thoracic spine in a child

  • Shuichiro Uehara
  • Takaharu Oue
  • Akihiro Yoneda
  • Yoshiko Hashii
  • Hideaki Ohta
  • Masahiro Fukuzawa
Case Report


An 8-year-old boy was referred due to difficulty in walking. T1-weighted MRI detected a well-marginated lesion expanding from the epidural region in the spinal canal to the paravertebral area through the Th9 and Th10 intervertebral foramen. The patient underwent a biopsy under video-assisted thoracoscopy and the tumor was diagnosed as Ewing’s sarcoma family of tumor (ESFT). Imaging confirmed that the tumor completely disappeared and his neurologic functions were recovered perfectly at the end of treatment. Very few cases of skeletal ESFT of epidural extension in childhood have been documented. Video-assisted thoracoscopic surgery remains the best option for the diagnosis of endothoracic tumors in children.


Ewing’s sarcoma family of tumor (ESFT) Dumbbell-shaped Video-assisted thoracoscopic surgery (VATS) Biopsy EWS-FLI1 


  1. 1.
    Iwamoto Y (2007) Diagnosis and treatment of Ewing’s sarcoma. Jpn J Clin Oncol 37:79–89. doi:10.1093/jjco/hyl142 PubMedCrossRefGoogle Scholar
  2. 2.
    Dorfman HD, Czerniak B (1995) Bone cancers. Cancer 75:203–210. doi:10.1002/1097-0142(19950101)75:1+<203::AID-CNCR2820751308>3.0.CO;2-VPubMedCrossRefGoogle Scholar
  3. 3.
    Ilaslan H, Sundaram M, Unni KK, Dekutoski MB (2004) Primary Ewing’s sarcoma of the vertebral column. Skeletal Radiol 33:506–513. doi:10.1007/s00256-004-0810-x PubMedCrossRefGoogle Scholar
  4. 4.
    Rose JS, Hermann G, Mendelson DS, Ambinder EP (1983) Extraskeletal Ewing sarcoma with computed tomography correlation. Skeletal Radiol 9:234–237. doi:10.1007/BF00354123 PubMedCrossRefGoogle Scholar
  5. 5.
    Uesaka T, Amano T, Inamura T, Ikezaki K, Inoha S, Takamatsu M et al (2003) Intradural, extramedullary spinal Ewing’s sarcoma in childhood. J Clin Neurosci 10:122–125. doi:10.1016/S0967-5868(02)00279-5 PubMedCrossRefGoogle Scholar
  6. 6.
    Song X, Choi J, Rao C, Nallu S, Nicastri AD (2008) Primary Ewing sarcoma of lumbar spine with massive intraspinal extension. Pediatr Neurol 38:58–60. doi:10.1016/j.pediatrneurol.2007.09.003 PubMedCrossRefGoogle Scholar
  7. 7.
    Koizumi K, Haraguchi S, Mikami I, Kubokura H, Okada D, Yamagishi S et al (2005) Video-assisted thoracic surgery for Ewing’s sarcoma of the mediastinum in a 3-year-old girl. Ann Thorac Cardiovasc Surg 11:117–120PubMedGoogle Scholar
  8. 8.
    Ozawa H, Kokubun S, Aizawa T, Hoshikawa T, Kawahara C (2007) Spinal dumbbell tumors: an analysis of a series of 118 cases. J Neurosurg Spine 7:587–593. doi:10.3171/SPI-07/12/587 PubMedCrossRefGoogle Scholar
  9. 9.
    Horowitz ME, Malawer MM, Delaney TF, Tsokos MG (1993) Ewing’s sarcoma family of tumors: Ewing’s sarcoma of bone and soft tissue and the peripheral primitive neuroectoermal tumors. Lippincott, PhiladelphiaGoogle Scholar
  10. 10.
    Delattre O, Zucman J, Melot T, Garau XS, Zucker JM, Lenoir GM et al (1994) The Ewing family of tumors—a subgroup of small-round-cell tumors defined by specific chimeric transcripts. N Engl J Med 331:294–299. doi:10.1056/NEJM199408043310503 PubMedCrossRefGoogle Scholar
  11. 11.
    Rescorla FJ, West KW, Gingalewski CA, Engum SA, Scherer LR 3rd, Grosfeld JL (2000) Efficacy of primary and secondary video-assisted thoracic surgery in children. J Pediatr Surg 35:134–138PubMedCrossRefGoogle Scholar
  12. 12.
    Smith TJ, Rothenberg SS, Brooks M, Bealer J, Chang J, Cook BA et al (2002) Thoracoscopic surgery in childhood cancer. J Pediatr Hematol Oncol 24:429–435. doi:10.1097/00043426-200208000-00004 PubMedCrossRefGoogle Scholar
  13. 13.
    Sailhamer E, Jackson CC, Vogel AM, Kang S, Wu Y, Chwals W et al (2003) Minimally invasive surgery for pediatric solid neoplasm. Am Surg 69:566–568PubMedGoogle Scholar
  14. 14.
    Klein SL, Sanford RA, Muhlbauer MS (1991) Pediatric spinal epidural metastases. J Neurosurg 74:70–75PubMedCrossRefGoogle Scholar
  15. 15.
    Lewis DW, Packer RJ, Raney B, Rak IW, Belasco J, Lange B (1986) Incidence, presentation, and outcome of spinal cord disease in children with systemic cancer. Pediatrics 78:438–443PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Shuichiro Uehara
    • 1
  • Takaharu Oue
    • 1
  • Akihiro Yoneda
    • 1
  • Yoshiko Hashii
    • 2
  • Hideaki Ohta
    • 2
  • Masahiro Fukuzawa
    • 1
  1. 1.Department of Pediatric SurgeryOsaka University Graduate School of MedicineOsakaJapan
  2. 2.Department of PediatricsOsaka University Graduate School of MedicineOsakaJapan

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