Child's Nervous System

, Volume 14, Issue 6, pp 288–291

Favorable outcome of giant cell glioblastoma in a child Report of an 11-year survival period

Report of an 11-year survival period
  • Rüdiger Klein
  • Gabriele Mölenkamp
  • Niels Sörensen
  • Wolfgang Roggendorf
CASE REPORT

Abstract

Giant cell glioblastomas are defined as glioblastomas with a marked predominance of bizarre, multinucleated giant cells. They represent about 5% of all glioblastomas and can occur at any site of the central nervous system, but the temporal and frontal lobes are the sites of predilection. Overall, giant cell glioblastomas show a prolonged survival period compared with common glioblastoma multiforme, and survival periods of 7 and 9 years have been reported in adults. Here we report on a child aged 11 years at diagnosis, who has so far survived for 11 years since operation and adjunctive radio- and chemotherapy.

Key words Glioblastoma Giant cells Prognosis Childhood Surgery Brain tumors 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • Rüdiger Klein
    • 1
  • Gabriele Mölenkamp
    • 2
  • Niels Sörensen
    • 3
  • Wolfgang Roggendorf
    • 1
  1. 1.Division Neuropathology, Institute of Pathology, University of Würzburg, Josef-Schneider-Strasse 2, D-97080 Würzburg, Germany Tel.: +49-931-201-3425 Fax: +49-931-201-3524Germany
  2. 2.Department of Pediatrics, University of Münster, Münster, GermanyGermany
  3. 3.Department of Pediatric Neurosurgery, University of Würzburg, D-97080 Würzburg, GermanyGermany

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