A rare case of pediatric moyamoya disease with reversible white matter lesions in a 3-year-old Chinese girl

  • Shi-Jun Li
  • Jie Xiong
  • Yu He
  • Yang-Yang Xiao
  • Ding-An Mao
  • Li-Qun LiuEmail author
Case Report


Moyamoya disease is a chronic cerebral vascular disease characterized by progressive occlusion of the cerebral arteries and resulting in the development of abnormal collateral circulation. We report a case of moyamoya disease in a 3-year-old Chinese girl with partly reversible white matter lesions. This case indicates that, in pediatric moyamoya disease, white matter lesions may be associated with cerebral ischemia, and they may be reversible after treatment.


Moyamoya disease Intermittent mental abnormality White matter lesion Collateral circulation 



Moyamoya disease


magnetic resonance angiography


digital substraction angiography


diffusion-weighted imaging


magnetic resonance imaging


fluid attenuated inversion recovery


susceptibility-weighted imaging


magnetic resonance spectroscopy


cerebral blood flow


Compliance with ethical standards

Conflict of interest

Th authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Pediatrics, the Second Xiangya HospitalCentral South UniversityChangshaChina
  2. 2.Department of Radiology, the Second Xiangya HospitalCentral South UniversityChangshaChina

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