Extensive reversible myelopathy secondary to acute quadriventricular noncommunicating hydrocephalus
Hydrocephalus is an active distension of the ventricular system due to various causes. Here, we want to share our experience of a 3.5-year-old girl with acute hydrocephalus and radiologic abnormality of the spinal cord from an underdiagnosed etiology. She was born at 34 weeks of gestation via cesarean section in a primigravida mother. Pregnancy was complicated by intrauterine growth retardation, maternal gestational diabetes, and preeclampsia. There was no family history of any neurodevelopmental diseases. She spent approximately 4 weeks in a neonatal care unit for feeding difficulties and then had repeated admissions in the hospital in early infancy due to failure to gain weight. She was also noted to have facial dysmorphisms, microcephaly, hypotonia, and global developmental delays. A comprehensive workup was completed including brain magnetic resonance imaging (MRI), extensive metabolic workup, and chromosome microarray testing. Her MRI brain at the age of 6 months...
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Conflict of interest
The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participant included in the study.