Child's Nervous System

, Volume 35, Issue 11, pp 2023–2026 | Cite as

Extensive reversible myelopathy secondary to acute quadriventricular noncommunicating hydrocephalus

  • Yohei Harada
  • Raghu Ramakrishnaiah
  • Kapil Arya
  • Debopam SamantaEmail author
Letter to the Editor

Dear Editor:

Hydrocephalus is an active distension of the ventricular system due to various causes. Here, we want to share our experience of a 3.5-year-old girl with acute hydrocephalus and radiologic abnormality of the spinal cord from an underdiagnosed etiology. She was born at 34 weeks of gestation via cesarean section in a primigravida mother. Pregnancy was complicated by intrauterine growth retardation, maternal gestational diabetes, and preeclampsia. There was no family history of any neurodevelopmental diseases. She spent approximately 4 weeks in a neonatal care unit for feeding difficulties and then had repeated admissions in the hospital in early infancy due to failure to gain weight. She was also noted to have facial dysmorphisms, microcephaly, hypotonia, and global developmental delays. A comprehensive workup was completed including brain magnetic resonance imaging (MRI), extensive metabolic workup, and chromosome microarray testing. Her MRI brain at the age of 6 months...


Compliance with ethical standards

Conflict of interest

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participant included in the study.


  1. 1.
    Kasapas K, Varthalitis D, Georgakoulias N, Orphanidis G (2015 Jan) Hydrocephalus due to membranous obstruction of Magendie’s foramen. J Korean Neurosurg Soc 57(1):68CrossRefGoogle Scholar
  2. 2.
    Sartoretti-Schefer S, Kollias S, Valavanis A (2000 Apr 1) Transient oedema of the cervical spinal cord. Neuroradiology. 42(4):280–284CrossRefGoogle Scholar
  3. 3.
    Humphries WE, Grossi PM, Liethe LG, George TM (2007 Jan) Ventriculoperitoneal shunt failure causing myelopathy in a patient with bilateral jugular vein occlusion: case report. J Neurosurg Spine 6(1):60–63CrossRefGoogle Scholar
  4. 4.
    Fischbein NJ, Dillon WP, Cobbs C, Weinstein PR (1999 Jan 1) The “presyrinx” state: a reversible myelopathic condition that may precede syringomyelia. Am J Neuroradiol 20(1):7–20PubMedGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Yohei Harada
    • 1
  • Raghu Ramakrishnaiah
    • 2
    • 3
  • Kapil Arya
    • 3
  • Debopam Samanta
    • 3
    Email author
  1. 1.Department of NeurologyUniversity of Arkansas for Medical SciencesLittle RockUSA
  2. 2.Division of Neuroradiology and Pediatric RadiologyUniversity of Arkansas for Medical SciencesLittle RockUSA
  3. 3.Department of Pediatrics, Section of Child NeurologyArkansas Children’s Hospital and University of Arkansas for Medical SciencesLittle RockUSA

Personalised recommendations