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The 100 most-cited articles about diffuse intrinsic pontine glioma: a bibliometric analysis

  • Victor M. LuEmail author
  • Erica A. Power
  • Panogiotis Kerezoudis
  • David J. DanielsEmail author
Original Article

Abstract

Purpose

Although the dismal clinical prognosis of diffuse intrinsic pontine glioma (DIPG) has not changed, there has been significant progress in the academic literature made in the biological understanding of this brainstem tumor. The aim of this analysis was to evaluate citation and other bibliometric characteristics of the 100 most-cited DIPG articles in the current literature in order to better understand the current state of our academic efforts in this area.

Methods

Elsevier’s Scopus database was searched for the 100 most-cited articles that focussed on DIPG. Articles were dichotomized as either primarily basic science (BSc) or clinical (CL) articles. Various bibliometric parameters were summarized and comparison between BSc and CL articles was performed using Pearson’s chi-square and Mann–Whitney U tests.

Results

Of the 100 most-cited articles, 36 (36%) were BSc and 64 (64%) were CL articles. Overall median values were as follows: citation count, 52 (range, 27–261); citation rate per year, 8.6 (range, 1.7–104); number of authors, 9 (range, 1–63); and publication year, 2011 (range, 1997–2017). Articles were published in a total of 43 different journals and predominately originated in the USA (n = 67, 67%). When compared with CL articles, BSc articles reported significantly greater citation count (P = 0.03), citations rate per year (P < 0.01), number of authors (P < 0.01), and more recent years of publication (P < 0.01).

Conclusions

The 100 most-cited articles about DIPG were characterized in this analysis. Although smaller in overall proportion, BSc articles demonstrated significantly increased bibliometric parameters, supporting the recent dominance of BSc in this field, primarily involving histone biology of the H3K27M mutation. Moving forward, it will be of great interest to see how the findings of these high-impact BSc articles will translate into future high-impact CL articles.

Keywords

Diffuse intrinsic pontine glioma H3 K27M Bibliometric analysis Brainstem Pediatric Glioma 

Notes

Funding

EAP was supported by CTSA Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS).

Compliance with ethical standards

Conflict of interest

Other authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this study.

Supplementary material

381_2019_4254_MOESM1_ESM.docx (36 kb)
ESM 1 (DOCX 36 kb)

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© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Neurologic SurgeryMayo ClinicRochesterUSA

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