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Child's Nervous System

, Volume 35, Issue 2, pp 363–368 | Cite as

Primitive myxoid mesenchymal tumor of infancy with brain metastasis: first reported case

  • Amna Afzal Saeed
  • Quratulain Riaz
  • Nasir Ud Din
  • Sadaf AltafEmail author
Case Report

Abstract

Introduction

Primitive myxoid mesenchymal tumor of infancy (PMMTI) is a recently diagnosed entity, with only a handful of cases reported to date.

Case description

Herein, we present the occurrence of this tumor in a 2-year-old boy, initially diagnosed as primitive neuroectodermal tumor of the extremity and treated with chemotherapy and surgical resection. He later presented with a cerebellar lesion, and biopsy was consistent with PMMTI.

Conclusion

While there have been previous cases of PMMTI reported with loco-regional metastatic spread, to our knowledge, there is no known incidence of distant metastasis with involvement of the central nervous system, which makes this case the first of its kind.

Keywords

Primitive myxoid mesenchymal tumor of infancy Metastasis Brain involvement 

Notes

Acknowledgements

The authors acknowledge the pathologists of St. Jude Children’s Research Hospital for reviewing the slides and performing molecular studies.

Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Medical CollegeAga Khan UniversityKarachiPakistan
  2. 2.Department of Pediatric OncologyAga Khan University HospitalKarachiPakistan
  3. 3.Department of Pathology and Laboratory MedicineAga Khan University HospitalKarachiPakistan

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