Limited dorsal myeloschisis with no extradural stalk linking to a flat skin lesion: a case report
- 49 Downloads
Limited dorsal myeloschisis (LDM) is characterized by a fibroneural stalk linking the skin lesion to the underlying spinal cord.
A 7-month-old girl with a lumbosacral “cigarette-burn” flat skin lesion underwent untethering surgery. The intradural tethering stalk appeared to originate at the dural wall and join the cord with no extradural stalk linking to the skin lesion. Histological examination of the intradural stalk revealed glial fibrillary acidic protein-immunopositive neuroglial tissues in the fibrocollagenous band, which is the central histopathological feature of an LDM stalk.
It is conceivable that the LDM stalk in our patient was originally linked to the skin lesion and subsequently regressed and was replaced by mature adipose tissue. We should be mindful of possible variations in the morphological features of LDM.
KeywordsGlial fibrillary acidic protein Fibroneural stalk Untethering
We thank Jane Charbonneau, DVM, from Edanz Group (www.edanzediting.com/ac) for editing a draft of this manuscript.
This work was partly supported by the Research Foundation of Fukuoka Children’s Hospital.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- 2.Lee JY, Park S-H, Chong S, Phi JH, Kim S-K, Cho B-K, Wang K-C (2018) Congenital dermal sinus and limited dorsal myeloschisis: “Spectrum disorders” of incomplete dysjunction between cutaneous and neural ectoderms. Neurosurgery (Epub ahead of print)Google Scholar
- 4.Morioka T, Suzuki SO, Murakami N, Mukae N, Shimogawa T, Haruyama H, Kira R, Iihara K (2018) Surgical histopathology of limited dorsal myeloschisis with flat skin lesion. Childs Nerv Syst (Epub ahead of print)Google Scholar
- 6.Murakami N, Morioka T, Hashiguchi K, Yoshiura T, Hiwatashi K, Suzuki SO, Nakamizo A, Amano T, Hata N, Sasaki T (2013) Usefulness of three-dimensional T1-weighted spoiled gradient-recalled echo and three-dimensional heavily T2-weighted images in preoperative evaluation of spinal dysraphism. Childs Nerv Syst 29:1905–1914CrossRefPubMedGoogle Scholar