A case of central nervous system vasculitis presenting as a mass-like lesion

  • AnneMarie M. DennyEmail author
  • Sumit K. Das
Case Report


Vasculitis of the central nervous system presenting as a mass lesion is a relatively uncommon occurrence. Even more uncommon is a vasculitis mimicking a demyelinating lesion. We present here an interesting case of a 15-year-old boy who was found to have a mass-like lesion on neuroimaging involving the left subcortical white matter and deep gray matter. The differential diagnosis for this lesion was primary demyelination versus a glial tumor, the former being more favored over the latter. Biopsy of this lesion however revealed findings compatible with a vasculitis, which was unexpected given the neuroimaging findings. To the authors’ knowledge, case reports in the English literature of a vasculitic lesion mimicking demyelination are scarce. This case also serves as a reminder of the diagnostic difficulty that arises in a pediatric patient with an initial presentation of mass-like lesion.


Primary angiitis of the central nervous system (PACNS) Vasculitis Mass lesion Tumor-like lesion Demyelinating 


Compliance with ethical standards

Conflict of interest

The authors have no conflicts of interest to report.


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© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Division of Pediatric NeurologyUniversity of Alberta HospitalEdmontonCanada
  2. 2.Division of NeuropathologyUniversity of Alberta HospitalEdmontonCanada

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