Child's Nervous System

, Volume 33, Issue 9, pp 1459–1462 | Cite as

A comprehensive review of the foramina of Luschka: history, anatomy, embryology, and surgery

  • Jaspreet Johal
  • Phillip Barrett Paulk
  • Peter C. Oakes
  • Rod J. Oskouian
  • Marios Loukas
  • R. Shane Tubbs
Review Paper



The purpose of this review is to comprehensively review the foramina of Luschka in regard to their discovery, embryology, anatomy, and surgical relevance.


This subject review of the foramina of Luschka was composed after conducting a thorough review of the available literature on this topic using PubMed and other primary sources.


The foramina of Luschka are paired apertures located in the lateral recesses of the fourth ventricle, within the posterior cranial fossa. The foramina of Luschka are of importance clinically as their blockage can disrupt the flow of cerebrospinal fluid leading to the development of hydrocephalus. These apertures were first described by the German anatomist Hubert von Luschka in the nineteenth century. These foramina are thought to emerge at around the 26th week of development. The apertures project into the cerebellopontine angle at the lateral border of the pontomedullary sulcus.


The foramina of Luschka may be surgically manipulated for the excision of tumors involving the fourth ventricle and surrounding structures and accessed for cochlear nucleus stimulation.


Dandy-Walker syndrome Hydrocephalus Cerebral ventricles Fourth ventricle 


Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.


  1. 1.
    Tubbs RS, Vahedi P, Loukas M, Shoja M, Cohen-Gadol AA (2011) Hubert von Luschka (1820–1875): his life, discoveries, and contributions to our understanding of the nervous system. J Neurosurg 114:268–272CrossRefPubMedGoogle Scholar
  2. 2.
    Takami H, Shin M, Kuroiwa M, Isoo A, Takahashi K, Saito N (2010) Hydrocephalus associated with cystic dilation of the foramina of Magendie and Luschka. J Neurosurg Pediatr 5:415–418CrossRefPubMedGoogle Scholar
  3. 3.
    Bokhari I, Rehman L, Hassan S, Hashim MS (2015) Dandy-Walker malformation: a clinical and surgical outcome analysis. J Coll Physicians Surg Pak 25:431–433PubMedGoogle Scholar
  4. 4.
    Luschka H (1855) Die Adergeflechte des menschlichen Gehirns. Verlag von Georg Reimer, BerlinGoogle Scholar
  5. 5.
    Blake JA (1900) The roof and lateral recesses of the fourth ventricle, considered morphologically and embryologically. J Comp Neurol 10:79–108CrossRefGoogle Scholar
  6. 6.
    Lang J (2001) Skull base and related structures: atlas of clinical anatomy, 2nd edn. Schattauer GmbH, StuttgartGoogle Scholar
  7. 7.
    Rhoton AL Jr (2007) Rhoton’s cranial anatomy and surgical approaches. Lippincott Williams & Wilkins, HagerstownGoogle Scholar
  8. 8.
    Sharifi M, Ungier E, Ciszek B, Krajewski P (2009) Microsurgical anatomy of the foramen of Luschka in the cerebellopontine angle, and its vascular supply. Surg Radiol Anat 31:431–437CrossRefPubMedGoogle Scholar
  9. 9.
    Horsburgh A, Kirollos RW, Massoud TF (2012) Bochdalek’s flower basket: applied neuroimaging morphometry and variants of choroid plexus in the cerebellopontine angles. Neuroradiology 54:1341–1346CrossRefPubMedGoogle Scholar
  10. 10.
    Perren F, Magistris MR (2014) Is hemifacial spasm accompanied by hemodynamic changes detectable by ultrasound? Acta Neurochir 156:1557–1560CrossRefPubMedGoogle Scholar
  11. 11.
    Ikezaki K, Matsushima T, Inoue T, Yokoyama N, Kaneko Y, Fukui M (1993) Correlation of microanatomical localization with postoperative survival in posterior fossa ependymomas. Neurosurgery 32:38–44CrossRefPubMedGoogle Scholar
  12. 12.
    Liu R, Kasper EM (2014) Bilateral telovelar approach: a safe route revisited for resections of various large fourth ventricle tumors. Surg Neurol Int 5:16CrossRefPubMedPubMedCentralGoogle Scholar
  13. 13.
    Torres-Corzo J, Sánchez-Rodríguez J, Cervantes D, Rodríguez-Della Vecchia R, Muruato-Araiza F, Hwang SW, Rangel-Castilla L (2014) Endoscopic transventricular transaqueductal Magendie and Luschka foraminoplasty for hydrocephalus. Neurosurgery 74:426–435CrossRefPubMedGoogle Scholar
  14. 14.
    Bento RF, Monteiro TA, Tsuji RK, Gomez MQ, Hausen Pinna M, Goffi-Gomez MV, Brito R (2012) Retrolabyrinthine approach for surgical placement of auditory brainstem implants in children. Acta Otolaryngol 132:462–466CrossRefPubMedGoogle Scholar
  15. 15.
    Kuroki A, Moller AR (1995) Microsurgical anatomy around the foramen of Luschka in relation to intraoperative recording of auditory evoked potentials from the cochlear nuclei. J Neurosurg 82:933–939CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  1. 1.Department of Anatomical Sciences, School of MedicineSt. George’s UniversitySt. GeorgeGrenada
  2. 2.Seattle Science FoundationSeattleUSA

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